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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Analysis of malachite green and metabolites in fish using liquid chromatography atmospheric pressure chemical ionization mass spectrometry.
 
Authors:  Doerge DR, Churchwell MI, Gehring TA, Pu YM, Plakas SM
 
Drug:  Malachite green
 
Fish species:  Catfish, channel
 
Date:  1998
 
Sample:  muscle
 
Ave Weight (gm):  500
 
Ave Water temp (°C):  25
 
Water:  Freshwater
 
Dosage:  1 ppm 1 h
 
Route:  BATH
 
Comments:  Residues 24 h post dosing MG=1030 ppb, LMG=590 ppb.
 
Metabolites:  Leucomalachite green, MG N-oxide, des-methyl LMG, 2des-methyl LMG, 3des-methyl LMG
 
Citation:  Rapid Communication in Mass Spectrometry 12:1625-34
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9807836&query_hl=11  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Organic-Dye
 
Wt gm-detail:  approx 0.5 kg
 
Water temp (°C)-detail:  25 C
 
Dosage-detail:  1 ppm hr
 
Method:  HPLC
 
Authors-red:  Doerge DR, Churchwell MI, Gehring TA, Pu YM, Plakas SM
 
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