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U.S. Department of Health and Human Services

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Title:  In vivo acetylcholinesterase inhibition, metabolism, and toxicokinetics of aldicarb in channel catfish: role of biotransformation in acute toxicity.
 
Authors:  Perkins EJ Jr, Schlenk D
 
Drug:  Aldicarb
 
Fish species:  Catfish, channel
 
Date:  2000
 
Sample:  blood, plasma
 
Ave Weight (gm):  750
 
Ave Water temp (°C):  22
 
Water:  Freshwater
 
Dosage:  38 ug/l up to 12 h
 
Route:  BATH
 
Comments:  (14C)-Aldecarb. Cannulated fish. Peak conc plateau around 6 hr 5.3 ng/ml.
 
Metabolites:  Sulfoxide, Sulfone
 
Citation:  Toxicological Sciences 53:308-315
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10696779  Opens a new window
 
Genus Species:  Ictalurus punctatus
 
Drug Class:  Carbamate-Pesticide
 
Wt gm-detail:  700-800
 
Water temp (°C)-detail:  18-25 C
 
Dosage-detail:  38 ug/l up to 12 h
 
Method:  HPLC-Rad
 
Authors-red:  Perkins EJ Jr, Schlenk D
 
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