Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Toxicokinetics of parathion and paraoxon in rainbow trout after intravascular administration and water exposure.
Authors:
Abbas R, Schultz IR, Doddapaneni S, Hayton WL
Drug:
Parathion
Fish species:
Trout, rainbow
Date:
1996
t1/2-hr:
57
Sample:
blood, plasma
Ave Weight (gm):
345
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
75 ng/ml up to 120 hrs
Route:
BATH
Comments:
Paraoxon is a metabolite of parathion; Parathion concentration reached approx1.0 ug/ml in first 24 hr then declined to 0.4 slowly over the next 100 hr.
Cl:
0.183 L/kg/h
Vd:
1.280 L/kg
Metabolites:
Paraoxon
Citation:
Toxicology and Applied Pharmacology 136:194-199
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8560474&dopt=Abstract
Genus Species:
Oncorhynchus mykiss
Drug Class:
Organic-Phosphorus-Pesticide
t1/2-detail:
57.3 h
Wt gm-detail:
140-550 g
Water temp (°C)-detail:
12 C
Dosage-detail:
75 ng/ml up to 120 hrs
Method:
GC
Authors-red:
Abbas R, Schultz IR, Doddapaneni S, Hayton WL
-
-