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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  2,3,7,8-Tetrachlorodibenzo-p-dioxin metabolism and disposition in yellow perch.
Authors:  Kleeman JM, Olson JR, Chen SM, Peterson RE (1986b)
Drug:  TCDD-(2,3,7,8-Tetrachlorodibenzo-p-dioxin)
Fish species:  Perch, American yellow
Date:  1986
t1/2-hr:  8232
Sample:  fat, abdominal
Ave Weight (gm):  5
Ave Water temp (°C):  18
Water:  Freshwater
Dosage:  494 pg TCDD/g diet 13 wks
Route:  PO
Comments:  t 1/2=24-49 wk. TCDD(3H).
Citation:  Toxicology and Applied Pharmacology 83:402-411
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3705070&dopt=Abstract  Opens a new window
Genus Species:  Perca flavescens
Drug Class:  Organic-Chlorinated-Pesticide
t1/2-detail:  24-49 wk
Wt gm-detail:  3-6g
Water temp (°C)-detail:  18 +/-2 C
Dosage-detail:  494 pg TCDD/g diet for 13 wks (494 ppt) (300 uCi, 28 Ci/ mmol)
Method:  Rad
Authors-red:  Kleeman JM, Olson JR, Chen SM, Peterson RE (1986b)