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PhishPharm - Detail

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Title:  Temperature dependence of Di-2-ethylhexyl phthalate (DEHP) pharmacokinetics in rainbow trout.
Authors:  Barron MG, Tarr BD, Hayton WL
Drug:  DEHP-(Di-2-Ethylhexyl Phthalate)
Fish species:  Trout, rainbow
Date:  1987
t1/2-hr:  80
Sample:  blood, plasma
Ave Weight (gm):  371
Ave Water temp (°C):  6
Water:  Freshwater
Dosage:  400 µg/kg sd
Route:  IVC
Comments:  For other parameters (t1/2) there are graphs, but no specific values, CL2= 17.7 ml/kg/hr, CL3= 1.1 ml/kg/hr
Citation:  Toxicology and Applied Pharmacology 88:305-312
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3576619&dopt=Abstract  Opens a new window
Genus Species:  Oncorhynchus mykiss
Drug Class:  Organic-Phtalate
t1/2-detail:  80 hr
Wt gm-detail:  371.1 g
Water temp (°C)-detail:  6 C
Dosage-detail:  400 µg/kg sd
Method:  Rad
Authors-red:  Barron MG, Tarr BD, Hayton WL