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U.S. Department of Health and Human Services

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Title:  Efficacy of florfenicol (Aquaflor®) medicated feed to control columnaris disease in juvenile Steelhead trout (Oncorhynchus mykiss).
 
Authors:  Foott JS, Stone R, Bowker J, Fogerty R
 
Drug:  Florfenicol
 
Fish species:  Trout, rainbow (steelhead)
 
Date:  2007
 
Sample:  viscera
 
Ave Weight (gm):  2.96
 
Ave Water temp (°C):  18
 
Water:  Freshwater
 
Dosage:  10 mg/kg 10d
 
Route:  PO
 
Comments:  Fish were fed at 2% body weight/day. Florfenicol concentration was less than 0.25ng (detectable level). Treatment was not successful in controlling columnaris. Test fish did not consume enough antibiotic in this trial. No significant pathological effect on posterior kidney, liver or intestine. Higher mouth and oral cavity infection might be due to lower feeding level. Trial 2 feed rates estimated within 6-16% of target level. 10mg/kg may be insufficient to rapidly control columnaris outbreaks.
 
Citation:  U.S. Fish and Wildlife- California Nevada Fish Health Center FY2007 investigational report.
 
Link:  http://www.fws.gov/canvfhc/reports.asp  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Phenicol
 
Wt gm-detail:  2.96 +/- 1.31g
 
Water temp (°C)-detail:  15.7 - 19.9 C
 
Dosage-detail:  10 mg/kg 10 d
 
Method:  Micro
 
Authors-red:  Foott JS, Stone R, Bowker J, Fogerty R
 
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