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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics of sulphadimethoxine in the lobster, Homarus americanus, following intrapericardial administration.
 
Authors:  Barron MG, Gedutis C, James MO
 
Drug:  Sulfadimethoxine
 
Fish species:  Lobster, American
 
Date:  1988
 
t1/2-hr:  72
 
Sample:  whole body
 
Ave Weight (gm):  500
 
Ave Water temp (°C):  14
 
Water:  Saltwater
 
Dosage:  42 mg/kg sd
 
Route:  IPC
 
Comments:  Male specimens. Central compartment analyzed
 
Protein binding:  0.535
 
Cl:  0.0139 L/kg/h
 
Vd:  0.70 L/kg
 
Citation:  Xenobiotica 18:269-276
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3381540&dopt=Abstract  Opens a new window
 
Genus Species:  Homarus americanus
 
Drug Class:  Antibiotic-Sulfa
 
t1/2-detail:  71.5 hours
 
Wt gm-detail:  400-600
 
Water temp (°C)-detail:  14 +/-1
 
Dosage-detail:  42 mg/kg sd
 
Method:  Rad
 
Authors-red:  Barron MG, Gedutis C, James MO
 
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