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U.S. Department of Health and Human Services

PhishPharm - Detail

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Title:  Pharmacokinetics of sulphadimethoxine in the lobster, Homarus americanus, following intrapericardial administration.
Authors:  Barron MG, Gedutis C, James MO
Drug:  Sulfadimethoxine
Fish species:  Lobster, American
Date:  1988
t1/2-hr:  74
Sample:  whole body
Ave Weight (gm):  500
Ave Water temp (°C):  14
Water:  Saltwater
Dosage:  42 mg/kg sd
Route:  IPC
Comments:  Female specimens. Peripheral compartment analyzed
Protein binding:  0.535
Cl:  0.014 L/kg/h
Vd:  0.61 L/kg
Citation:  Xenobiotica 18:269-276
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3381540&dopt=Abstract  Opens a new window
Genus Species:  Homarus americanus
Drug Class:  Antibiotic-Sulfa
t1/2-detail:  74.2 hours
Wt gm-detail:  400-600
Water temp (°C)-detail:  14 +/-1
Dosage-detail:  42 mg/kg sd
Method:  Rad
Authors-red:  Barron MG, Gedutis C, James MO