Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Metabolism and elimination of benzocaine by rainbow trout, Oncorhynchus mykiss.
Authors:
Meinertz JR, Gingerich WH, Allen JL
Drug:
Benzocaine
Fish species:
Trout, rainbow
Date:
1991
Sample:
gill
Ave Weight (gm):
650
Ave Water temp (°C):
12
Water:
Freshwater
Dosage:
20.8 ug/kg sd
Route:
IVC
Comments:
The radioactivty was measured in the water (urinary catheter kept urine out of water). Branchial elimination- 60% of dose in first 3 h
Metabolites:
N-acetylated benzocaine
Citation:
Xenobiotica 21:4:525-533
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1897251
Genus Species:
Oncorhynchus mykiss
Drug Class:
Anesthetic-Benzocaine
Wt gm-detail:
595-704 g
Water temp (°C)-detail:
12+/-0.9 C
Dosage-detail:
20.8 ug/kg sd
Method:
HPLC-Rad
Authors-red:
Meinertz JR, Gingerich WH, Allen JL
-
-