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U.S. Department of Health and Human Services

PhishPharm - Detail
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Title:  Pharmacokinetics, bioavailability, plasma protein binding and disposition of nalidixic acid in Rainbow trout (Oncorhynchus mykiss).
 
Authors:  Jarobe H, Toth BR, Shoemaker KE, Greenless KJ, Kleinow KM.
 
Drug:  Nalidixic acid
 
Fish species:  Trout, rainbow
 
Date:  1993
 
t1/2-hr:  46
 
Sample:  blood, plasma
 
Ave Weight (gm):  1196
 
Ave Water temp (°C):  14
 
Water:  Freshwater
 
Dosage:  5 mg/kg sd
 
Route:  PO
 
Comments:  (14 C)Naladixic acid. Bioavailabilty 106.5 %
 
Citation:  Xenobiotica 23:961-972
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8291264&dopt=Abstract  Opens a new window
 
Genus Species:  Oncorhynchus mykiss
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  45.2 h
 
Wt gm-detail:  1196+/- 105 g g
 
Water temp (°C)-detail:  14+-1 C
 
Dosage-detail:  5 mg/kg sd
 
Method:  HPLC-Rad
 
Authors-red:  Jarobe H, Toth BR, Shoemaker KE, Greenless KJ, Kleinow KM.
 
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