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U.S. Department of Health and Human Services

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Title:  Pharmacokinetics of a discontinuous absorption process of oxolinic acid in turbot, (Scophthalmus maximus), after a single oral administration.
 
Authors:  Poher I, Blanc G
 
Drug:  Oxolinic acid
 
Fish species:  Turbot
 
Date:  1998
 
t1/2-hr:  20
 
Sample:  blood, serum
 
Ave Weight (gm):  500
 
Ave Water temp (°C):  16
 
Water:  Saltwater
 
Dosage:  10 mg/kg sd
 
Route:  PO
 
Comments:  Bioavailabiltiy 27.9 %. PK not affected by sex.
 
Cl:  0.06 L/kg/h
 
Vc:  0.34 L/kg
 
Vd:  2.08 L/kg
 
Citation:  Xenobiotica 28:1061-1073
 
Link:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9879638&dopt=Abstract  Opens a new window
 
Genus Species:  Scophthalmus maximus
 
Drug Class:  Antibiotic-Quinolone
 
t1/2-detail:  20.4 h
 
Wt gm-detail:  500+/-40g
 
Water temp (°C)-detail:  16+/-0.2C
 
Dosage-detail:  10 mg/kg sd
 
Method:  HPLC
 
Authors-red:  Poher I, Blanc G
 
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