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Drugs@FDA: FDA-Approved Drugs

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New Drug Application (NDA): 018956
Company: GE HEALTHCARE
Drug Name Active Ingredients Strength Dosage Form/Route Marketing Status TE Code RLD RS
OMNIPAQUE 12 IOHEXOL 2.6% SOLUTION;ORAL Prescription None Yes Yes
OMNIPAQUE 140 IOHEXOL 30.2% INJECTABLE;INJECTION Prescription None Yes Yes
OMNIPAQUE 180 IOHEXOL 38.8% SOLUTION;INJECTION, ORAL, RECTAL Prescription None Yes Yes
OMNIPAQUE 210 IOHEXOL 45.3% INJECTABLE;INJECTION Discontinued None No No
OMNIPAQUE 240 IOHEXOL 51.8% SOLUTION;INJECTION, ORAL, RECTAL Prescription None Yes Yes
OMNIPAQUE 300 IOHEXOL 64.7% SOLUTION;INJECTION, ORAL, RECTAL Prescription AP Yes Yes
OMNIPAQUE 350 IOHEXOL 75.5% SOLUTION;INJECTION, ORAL Prescription None Yes Yes
OMNIPAQUE 70 IOHEXOL 15.1% SOLUTION;URETHRAL Discontinued None No No
OMNIPAQUE 9 IOHEXOL 1.9% SOLUTION;ORAL Prescription None Yes Yes
Original Approvals or Tentative Approvals
Action Date Submission Action Type Submission Classification Review Priority; Orphan Status Letters, Reviews, Labels, Patient Package Insert Notes Url
12/26/1985 ORIG-1 Approval Type 1 - New Molecular Entity STANDARD

Label is not available on this site.

Supplements
Action Date Submission Supplement Categories or Approval Type Letters, Reviews, Labels, Patient Package Insert Note Url
10/08/2024 SUPPL-119 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/018956Orig1s119,020608Orig1s047lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2024/018956Orig1s119, 020608Orig1s047ltr.pdf
04/25/2023 SUPPL-116 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/018956s116,020608s049lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2023/018956Orig1s116;020608Orig1s049ltr.pdf
02/18/2022 SUPPL-113 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/018956s113,020608s045lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2022/018956Orig1s113; 020608Orig1s045ltr.pdf
08/05/2021 SUPPL-112 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/018956s112lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2021/018956Orig1s112ltr.pdf
11/04/2020 SUPPL-108 Labeling-Container/Carton Labels Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018956Orig1s108lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2020/018956Orig1s108ltr.pdf
07/02/2020 SUPPL-105 Labeling-Container/Carton Labels, Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018956s105lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2020/018956Orig1s105ltr.pdf
04/17/2018 SUPPL-101 Labeling-Container/Carton Labels, Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/018956s101lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2018/018956Orig1s101ltr.pdf
04/05/2017 SUPPL-99 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018956s099lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2017/018956Orig1s099,020608s036s037ltr.pdf
10/21/2015 SUPPL-96 Manufacturing (CMC)

Label is not available on this site.

07/06/2015 SUPPL-95 Labeling-Package Insert Label (PDF)
Letter (PDF)
https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/018956s095,020608s031lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2015/018956Orig1s095,020608Orig1s031ltr.pdf
03/03/2015 SUPPL-94 Manufacturing (CMC)

Label is not available on this site.

06/19/2014 SUPPL-93 Manufacturing (CMC)

Label is not available on this site.

11/20/2013 SUPPL-92 Manufacturing (CMC)

Label is not available on this site.

02/10/2014 SUPPL-91 Manufacturing (CMC)

Label is not available on this site.

08/21/2013 SUPPL-89 Manufacturing (CMC)

Label is not available on this site.

10/01/2007 SUPPL-76 Labeling Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2007/018956s076ltr.pdf
03/25/2005 SUPPL-65 Manufacturing (CMC) Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2005/18956s065ltr.pdf
12/27/2004 SUPPL-62 Labeling Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2004/18956s062ltr.pdf
03/05/2004 SUPPL-58 Labeling Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2004/18956slr058ltr.pdf
11/20/2002 SUPPL-54 Manufacturing (CMC)

Label is not available on this site.

08/05/2002 SUPPL-53 Manufacturing (CMC)

Label is not available on this site.

12/19/2000 SUPPL-52 Manufacturing (CMC)-Control

Label is not available on this site.

09/08/1998 SUPPL-51 Manufacturing (CMC)-Control

Label is not available on this site.

12/23/2002 SUPPL-49 Labeling Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2002/18956slr049ltr.pdf
08/18/1995 SUPPL-46 Manufacturing (CMC)

Label is not available on this site.

11/04/1994 SUPPL-45 Manufacturing (CMC)

Label is not available on this site.

08/18/1995 SUPPL-44 Manufacturing (CMC)-Control

Label is not available on this site.

06/15/1995 SUPPL-43 Labeling Review (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/18956a_s043_061595.pdf
11/28/1995 SUPPL-42 Manufacturing (CMC)-Control

Label is not available on this site.

09/30/1994 SUPPL-41 Manufacturing (CMC)-Packaging

Label is not available on this site.

10/20/1992 SUPPL-40 Manufacturing (CMC)-Control

Label is not available on this site.

12/23/2002 SUPPL-39 Labeling Letter (PDF)

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2002/18956slr039ltr.pdf
09/30/1992 SUPPL-38 Manufacturing (CMC)

Label is not available on this site.

12/11/1992 SUPPL-37 Manufacturing (CMC)-Packaging

Label is not available on this site.

06/01/1994 SUPPL-36 Labeling

Label is not available on this site.

06/01/1994 SUPPL-35 Manufacturing (CMC)-Packaging

Label is not available on this site.

03/01/1993 SUPPL-34 Manufacturing (CMC)-Packaging

Label is not available on this site.

03/01/1993 SUPPL-33 Labeling

Label is not available on this site.

03/01/1993 SUPPL-32 Manufacturing (CMC)-Control

Label is not available on this site.

03/01/1993 SUPPL-31 Manufacturing (CMC)

Label is not available on this site.

12/04/1995 SUPPL-30 Manufacturing (CMC)-Control

Label is not available on this site.

08/24/1990 SUPPL-29 Manufacturing (CMC)-Packaging

Label is not available on this site.

07/13/1993 SUPPL-28 Efficacy-New Route Of Administration Review

Label is not available on this site.

https://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/018956-S28_Omnipaque_toc.html
03/26/1992 SUPPL-27 Manufacturing (CMC)-Control

Label is not available on this site.

11/30/1989 SUPPL-26 Efficacy-New Patient Population

Label is not available on this site.

05/03/1989 SUPPL-24 Labeling

Label is not available on this site.

07/28/1989 SUPPL-23 Efficacy-New Indication

Label is not available on this site.

07/28/1989 SUPPL-22 Efficacy-New Patient Population

Label is not available on this site.

06/30/1989 SUPPL-21 Efficacy-New Indication

Label is not available on this site.

06/30/1989 SUPPL-20 Efficacy-New Indication

Label is not available on this site.

01/04/1989 SUPPL-19 Manufacturing (CMC)-Control

Label is not available on this site.

03/31/1989 SUPPL-18 Efficacy-New Indication

Label is not available on this site.

11/30/1988 SUPPL-17 Efficacy-New Indication

Label is not available on this site.

04/18/1988 SUPPL-16 Manufacturing (CMC)

Label is not available on this site.

05/24/1988 SUPPL-15 Efficacy-New Indication

Label is not available on this site.

07/29/1988 SUPPL-14 Efficacy-New Indication

Label is not available on this site.

01/27/1988 SUPPL-13 Manufacturing (CMC)-Control

Label is not available on this site.

02/01/1988 SUPPL-12 Efficacy-New Patient Population

Label is not available on this site.

05/22/1989 SUPPL-10 Manufacturing (CMC)

Label is not available on this site.

05/12/1987 SUPPL-9 Efficacy-New Indication

Label is not available on this site.

12/23/1993 SUPPL-8 Manufacturing (CMC)

Label is not available on this site.

06/04/1987 SUPPL-7 Manufacturing (CMC)-Packaging

Label is not available on this site.

05/27/1987 SUPPL-6 Labeling

Label is not available on this site.

04/21/1987 SUPPL-4 Labeling

Label is not available on this site.

11/20/1986 SUPPL-3 Labeling

Label is not available on this site.

02/05/1987 SUPPL-2 Manufacturing (CMC)

Label is not available on this site.

11/26/1986 SUPPL-1 Efficacy-New Indication

Label is not available on this site.

Action Date Submission Supplement Categories or Approval Type Letters, Reviews, Labels,
Patient Package Insert
Note Url
10/08/2024 SUPPL-119 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/018956Orig1s119,020608Orig1s047lbl.pdf
04/25/2023 SUPPL-116 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/018956s116,020608s049lbl.pdf
02/18/2022 SUPPL-113 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/018956s113,020608s045lbl.pdf
08/05/2021 SUPPL-112 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/018956s112lbl.pdf
11/04/2020 SUPPL-108 Labeling-Container/Carton Labels Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018956Orig1s108lbl.pdf
07/02/2020 SUPPL-105 Labeling-Container/Carton Labels Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018956s105lbl.pdf
07/02/2020 SUPPL-105 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/018956s105lbl.pdf
04/17/2018 SUPPL-101 Labeling-Container/Carton Labels Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/018956s101lbl.pdf
04/17/2018 SUPPL-101 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/018956s101lbl.pdf
04/05/2017 SUPPL-99 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018956s099lbl.pdf
07/06/2015 SUPPL-95 Labeling-Package Insert Label (PDF) https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/018956s095,020608s031lbl.pdf

OMNIPAQUE 12

There are no Therapeutic Equivalents.

OMNIPAQUE 140

There are no Therapeutic Equivalents.

OMNIPAQUE 180

There are no Therapeutic Equivalents.

OMNIPAQUE 210

There are no Therapeutic Equivalents.

OMNIPAQUE 240

There are no Therapeutic Equivalents.

OMNIPAQUE 300

SOLUTION;INJECTION, ORAL, RECTAL; 64.7%
TE Code = AP

Drug Name Active Ingredients Strength Dosage Form/Route Marketing Status RLD TE Code Application No. Company
IOHEXOL IOHEXOL 64.7% SOLUTION;INJECTION, ORAL, RECTAL Prescription No AP 217737 AMNEAL
OMNIPAQUE 300 IOHEXOL 64.7% SOLUTION;INJECTION, ORAL, RECTAL Prescription Yes AP 018956 GE HEALTHCARE

OMNIPAQUE 350

There are no Therapeutic Equivalents.

OMNIPAQUE 70

There are no Therapeutic Equivalents.

OMNIPAQUE 9

There are no Therapeutic Equivalents.

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