FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

Current/Resolved Shortages
Discontinuations
Therapeutic Categories
New and Updated

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient	Status
Alogliptin Tablets	Currently in Shortage
Amino Acids	Resolved
Aminophylline Injection, USP	Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets	Currently in Shortage
Anagrelide Hydrochloride Capsules	Currently in Shortage
Asparaginase Erwinia Chrysanthemi (Erwinaze)	Currently in Shortage
Atropine Sulfate Injection	Currently in Shortage
Atropine Sulfate Ophthalmic Ointment	Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1%	Resolved
Bacitracin Ophthalmic Ointment	Currently in Shortage
Belatacept (Nulojix) Lyophilized Powder for Injection	Currently in Shortage
Bumetanide Injection, USP	Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection, USP	Currently in Shortage
Bupivacaine Hydrochloride Injection, USP	Currently in Shortage
Buspirone HCl Tablets	Resolved
Calcitriol Injection USP 1MCG /ML	Currently in Shortage
Calcium Chloride Injection, USP	Currently in Shortage
Capreomycin Injection, USP	Currently in Shortage
Carbidopa and Levodopa Extended Release Tablets	Resolved
Carisoprodol Tablets, USP	Currently in Shortage
Cefazolin Injection	Currently in Shortage
Cefepime Injection	Currently in Shortage
Cefotaxime Sodium Injection	Currently in Shortage
Cefotetan Disodium Injection	Currently in Shortage
Cefoxitin for Injection, USP	Currently in Shortage
Chloroquine Phosphate Tablets	Resolved
Cysteine Hydrochloride Injection	Resolved
Deferoxamine Mesylate for Injection, USP	Resolved
Dexamethasone Sodium Phosphate Injection	Currently in Shortage
Dexrazoxane Injection	Currently in Shortage
Dextrose 25% Injection	Currently in Shortage
Dextrose 5% Injection Bags	Resolved
Dextrose 50% Injection	Currently in Shortage
Diazepam Injection, USP	Resolved
Dicyclomine Oral Tablets/Capsules	Currently in Shortage
Difluprednate (Durezol) Ophthalmic Emulsion	Resolved
Diltiazem Hydrochloride	Currently in Shortage
Diltiazem Hydrochloride ER (Twice-a-Day) Capsules	Currently in Shortage
Diphenhydramine Injection	Currently in Shortage
Disulfiram Tablets	Currently in Shortage
Dobutamine Hydrochloride Injection	Currently in Shortage
Dopamine Hydrochloride Injection	Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution	Currently in Shortage
Dorzolamide Hydrochloride Ophthalmic Solution	Currently in Shortage
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution	Currently in Shortage
Enalaprilat Injection, USP	Currently in Shortage
Epinephrine Injection, 0.1 mg/mL	Currently in Shortage
Epinephrine Injection, Auto-Injector	Currently in Shortage
Eprosartan Mesylate Tablets	Currently in Shortage
Erythromycin Lactobionate for Injection, USP	Currently in Shortage
Erythromycin Ophthalmic Ointment	Currently in Shortage
Ethiodized Oil (Lipiodol) Injection	Resolved
Fentanyl Citrate (Sublimaze) Injection	Currently in Shortage
Fludrocortisone Acetate Tablets	Resolved
Fluorescein Injection	Currently in Shortage
Fluorescein Sodium and Benoxinate Hydrochloride Ophthalmic Solution	Resolved
Fluorescein Strips	Currently in Shortage
Flurazepam Hydrochloride Capsules	Currently in Shortage
Fluvoxamine ER Capsules	Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets	Currently in Shortage
Guanfacine Hydrochloride Tablets	Currently in Shortage
Haloperidol Tablets	Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection	Currently in Shortage
Hydromorphone Hydrochloride Injection, USP	Currently in Shortage
Hydroxyprogesterone Caproate Injection	Resolved
Hydroxyzine Pamoate Oral Capsules	Currently in Shortage
Imipenem and Cilastatin for Injection, USP	Currently in Shortage
Isocarboxazid Tablets	Resolved
Ketamine Injection	Currently in Shortage
Ketoprofen Capsules	Currently in Shortage
Ketorolac Tromethamine Injection	Currently in Shortage
Labetalol Hydrochloride Injection	Currently in Shortage
Latanoprost Ophthalmic Solution 0.005%	Currently in Shortage
Letermovir (Prevymis) Injection	Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection	Currently in Shortage
Leuprolide Acetate (Lupron Depot; Lupron Depot Ped) Injection	Resolved
Levetiracetam Extended-Release Oral Tablets, USP	Currently in Shortage
Levetiracetam Immediate-Release Oral Tablets, USP	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection	Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine	Currently in Shortage
Lorazepam Injection, USP	Currently in Shortage
Loxapine Capsules	Currently in Shortage
Methadone Hydrochloride Injection	Currently in Shortage
Methocarbamol Tablets	Resolved
Methotrexate Sodium Injection	Resolved
Methyldopa Tablets	Currently in Shortage
Methylphenidate Hydrochloride (QUILLICHEW ER) Extended-Release Chewable Tablets	Resolved
Methylphenidate Hydrochloride (QUILLIVANT XR) for Extended-Release Oral Suspension	Currently in Shortage
Metoclopramide Injection, USP	Resolved
Metoprolol Tartrate Injection, USP	Currently in Shortage
Metronidazole Injection, USP	Currently in Shortage
Morphine Sulfate Injection, USP	Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric)	Currently in Shortage
Nalbuphine Hydrochloride Injection	Currently in Shortage
Nelarabine (Arranon) Injection	Resolved
Nystatin Oral Suspension	Currently in Shortage
Olmesartan Medoxomil Tablets	Currently in Shortage
Ondansetron Hydrochloride Injection	Currently in Shortage
Oxytocin Injection, USP Synthetic	Currently in Shortage
Pantoprazole Sodium for Injection	Currently in Shortage
Parathyroid Hormone (Natpara) Injection	Currently in Shortage
Penicillamine (Depen) Titratable Tablets	Resolved
Pentamidine Isethionate (Nebupent) For Inhalation Solution	Resolved
Peritoneal Dialysis Solutions	Currently in Shortage
Phenytoin Sodium Injection, USP	Resolved
Physostigmine Salicylate Injection, USP	Currently in Shortage
Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Piperacillin and Tazobactam (Zosyn) Injection	Currently in Shortage
Potassium Acetate Injection, USP	Currently in Shortage
Potassium Chloride Injection	Resolved
Prednisolone Acetate 1% Ophthalmic Suspension	Resolved
Primaquine Phosphate Tablet, EQ 15mg Base	Resolved
Procainamide Hydrochloride Injection, USP	Currently in Shortage
Progesterone Injection, USP	Resolved
Promethazine (Phenergan) Injection	Currently in Shortage
Ranitidine Injection, USP	Currently in Shortage
Ranitidine Tablets/Capsules	Currently in Shortage
Remifentanil (Ultiva) Lyophilized Powder for Solution Injection	Currently in Shortage
Rocuronium Bromide Injection	Resolved
Ropivacaine Hydrochloride Injection	Currently in Shortage
Sclerosol Intrapleural Aerosol	Currently in Shortage
Scopolamine Transdermal System	Resolved
Sildenafil Citrate (REVATIO)	Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection	Currently in Shortage
Sodium Acetate Injection, USP	Currently in Shortage
Sodium Bicarbonate Injection, USP	Currently in Shortage
Sodium Chloride 0.9% Injection Bags	Resolved
Sodium Chloride 23.4% Injection	Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes	Currently in Shortage
Sodium Phosphate Injection	Resolved
Sterile Water	Resolved
Tacrolimus Capsules	Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA)	Currently in Shortage
Thioridazine Hydrochloride Tablets	Resolved
Thiothixene Capsules	Currently in Shortage
Timolol Maleate Tablets	Currently in Shortage
Triamcinolone Acetonide (Triesence) Injection, Suspension	Currently in Shortage
Trifluoperazine Hydrochloride Tablets	Resolved
Trifluridine Ophthalmic Solution	Currently in Shortage
Valsartan Tablets	Currently in Shortage
Vinblastine Sulfate Injection	Currently in Shortage
Vincristine Sulfate Injection, USP (Preservative-Free)	Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets	Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abciximab (ReoPro) Injection
Acarbose (Precose) Tablets
Acyclovir Capsules, USP
Acyclovir Tablets, USP
Albuterol Sulfate and Ipratropium Bromide Inhalation Solution
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amlodipine Besylate and Benazepril Hydrochloride Capsules
Amlodipine Besylate and Olmesartan Medoxomil Tablets
Amoxicillin Powder for Suspension
Anastrozole Tablets
Argatroban Injection
Atracurium Besylate Injection, USP
Avelox® (moxifloxacin HCl) Tablets
Azacitidine Injection
Benzyl Alcohol (Ulesfia) Lotion 5%
Bethanechol Chloride Tablets
Bosentan Tablets
Budesonide Capsules
Buprenorphine Hydrochloride Sublingual Tablets
Bupropion Hydrochloride (Zyban) Tablets
Bupropion Hydrochloride Extended-Release Tablets
Carbamazepine Extended Release Capsules
Carbidopa and Levodopa Extended Release Tablets
Carbinoxamine Maleate
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Carisoprodol Tablets, USP
Cefepime Injection
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Cetirizine Hydrochloride
Chlordiazepoxide Hydrochloride USP, Capsules
Chlorothiazide Tablets
Chlorpheniramine Maleate; Hydrocodone Bitartrate; Pseudoephedrine Hydrochloride Oral Solution
Chlorpropamide Tablets
Ciprofloxacin Extended-Release Tablets
Clindamycin Injection, USP
Clindamycin Phosphate and Benzoyl Peroxide (Duac) Topical Gel
Clomiphene Citrate
Clonazepam Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Delavirdine Mesylate (RESCRIPTOR) Tablets
Desloratadine Tablets
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dexmethylphenidate Hydrochloride Tablets
Dextroamphetamine Sulfate Extended-Release Capsules
Diclofenac Sodium Extended Release Tablets
Diclofenac Sodium Topical Gel
Dicyclomine Hydrochloride (BENTYL®) Capsule & Tablet
Didanosine Delayed-Release Capsules USP
Diethylpropion Hydrochloride Controlled-Release Tablets
Diethylpropion Hydrochloride Tablets
Diltiazem Hydrochloride
Diltiazem Hydrochloride Extended-Release Capsules
Disulfiram Tablets
Divalproex Sodium Extended-Release Tablets
Docusate Sodium Capsules, USP
Donepezil Hydrochloride Tablets
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxycycline Capsules
Doxycycline Hyclate Capsules
Doxycycline Hyclate Delayed Release Tablets
Dronabinol Capsules
Dutasteride Capsules
Entecavir Tablets
Epinastine Hydrochloride (Elestat®) Ophthalmic Solution
Epirubicin Hydrochloride Injection
Eptifibatide (Integrilin) Injection
Escitalopram (Lexapro) 5 mg/5 mL Oral Solution
Ethinyl Estradiol and Levonorgestrel (Myzilra)
Ethosuximide Oral Solution, USP
Etoposide Injection
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Fenofibric Acid Delayed-Release Capsules
Finasteride Tablets
Fludarabine Phosphate for Injection, USP
Flumazenil Injection
Fluorouracil Injection
Fluoxetine Capsules
Fluphenazine Hydrochloride Tablets
Flurbiprofen Tablets
Flutamide Capsules, USP
Fluvastatin Sodium Extended-Release Tablets
Folic Acid Tablets, USP
Gadopentetate Dimeglumine (Magnevist) Injection
Gatifloxacin Ophthalmic Solution
Gemcitabine Hydrochloride Injection
Glimepiride Tablets
Guanfacine Hydrochloride Extended-Release Tablets
Hydrochlorothiazide (Microzide) Capsules
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocortisone Acetate Suppository
Hydrocortisone Tablets, USP
Hydromorphone Hydrochloride Extended-Release Tablets, CII
Ifosfamide/Mesna Kit
Indomethacin Capsules
INTRON A (Interferon alfa-2b) Recombinant for Injection
Isosorbide Mononitrate Extended-Release Tablets, USP
Ketoconazole Tablets
Ketoprofen Capsules
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lamotrigine Tablets
Lanoxin (digoxin) Tablets
Lesinurad (ZURAMPIC) Tablets
Lesinurad/Allopurinol (DUZALLO®) Tablets
Levetiracetam Extended-Release Oral Tablets, USP
Levetiracetam Oral Tablets, USP
Levocetirizine Dihydrochloride Tablets
Levoleucovorin Calcium Injection
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril (Prinivil) Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Medroxyprogesterone Acetate (Provera) Tablet
Megestrol Acetate (Megace) Oral Suspension
Mesna Injection
Metaproterenol Sulfate Tablets, USP
Metformin Hydrochloride (Glucophage XR) Tablets Extended Release
Metformin Hydrochloride (Glucophage) Tablets
Metformin Hydrochloride Extended Release Tablets
Methocarbamol Tablet, USP
Methotrexate Sodium Injection
Methotrexate Tablets, USP
Methscopolamine Bromide Tablets
Methscopolamine Bromide, Tablets, USP
Methyclothiazide Tablets
Methyldopa Tablets
Methylphenidate Hydrochloride Extended-Release Tablets, USP CII
Methylphenidate Hydrochloride Tablets, USP CII
Methylprednisolone Tablets
Metoprolol Tartrate Tablets
Mirtazapine Orally Disintegrating Tablets
Mirtazapine Tablets, USP
Modafinil Tablets
Mometasone Furoate (Elocon) Topical Cream
Montelukast Sodium Tablets
Morphine Sulfate and Naltrexone Hydrochloride (EMBEDA®) Extended-Release Capsules
Morphine Sulfate Extended-Release Tablets
Morphine Sulfate Injection, USP
Mupirocin Calcium Nasal Ointment
Nafcillin Sodium Injection
Naftifine Hydrochloride Cream
Naratriptan Hydrochloride Tablets
Neomycin and Polymyxin B Sulfates Solution For Irrigation, USP
Nesiritide Powder (NATRECOR) for Injection
Nevirapine Extended Release Tablets
Nifedipine Extended-Release Tablet, USP
Nizatidine Capsules
Norethindrone (NOR QD) Tablets
Norethindrone and Ethinyl Estradiol and Ferrous Fumarate Tablets
Nystatin Cream, USP
Olaratumab (Lartruvo) Injection
Olmesartan Medoxomil and Hydrochlorothiazide Tablets
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Omega-3-Acid Ethyl Esters
Omeprazole Delayed-Release 40 mg Capsules
Oxybutynin Chloride Extended-Release Tablets
Oxycodone Hydrochloride Tablets
Oxymorphone Hydrochloride
Oxytocin (Pitocin) Synthetic Injection, USP
Paclitaxel Injection, USP
Peginterferon alfa-2b (Sylatron)
PEGINTRON (peginterferon alfa-2b) Injection
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Pramipexole Dihydrochloride Extended Release Tablets
Primidone Tablets, USP
Promethazine Hydrochloride Injection, Solution
Quinapril Hydrochloride (Accupril) Tablets
Quinidine Gluconate Injection
Rabeprazole Sodium Delayed-Release Tablets
Repaglinide Tablets
Ribavirin (Rebetol) Oral Solution
Ribavirin Capsules and Tablets
Risedronate Sodium Tablets
Risedronate Tablets
Risperidone Tablets
Rizatriptan Benzoate Orally Disintegrating Tablets
Ropinirole Hydrochloride Extended Release (Requip XL) Tablets
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Sodium Lactate Injection, USP
Sotalol Hydrochloride Tablets
Spironolactone Tablets
Spironolactone Tablets, USP
Stavudine Capsules
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Technetium Tc99m Succimer Injection (DMSA)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide (TEMODAR) Capsules
Testosterone Buccal System
Testosterone Gel 1%
Tizanidine Hydrochloride Tablets
Tolazamide Tablets
Tolbutamide Tablets
Tolterodine Tartrate (Detrol LA) Extended Release Capsules
Tositumomab and Iodine I 131 Tositumomab (Bexxar)
Trandolapril Tablets
Tranexamic Acid Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide (Dyazide) Capsules
Triamterene and Hydrochlorothiazide Tablets
Valacyclovir Hydrochloride Tablets
Valsartan Tablets
Vardenafil Hydrochloride (Levitra) Tablets
Verapamil HCl Extended-Release Tablets
Verapamil Hydrochloride Extended-Release Tablets and Capsules
Verapamil Hydrochloride Tablets
Vincristine Sulfate (VINCASAR PFS) Injection, USP
Vinorelbine Tartrate Injection
Zoledronic Acid Injection
Zolpidem Tartrate Extended Release Tablets
Zolpidem Tartrate Tablets