FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient Status
Alogliptin Tablets Currently in Shortage
Amifostine Injection Currently in Shortage
Amino Acids Resolved
Aminophylline Injection, USP Currently in Shortage
Amoxapine Tablets Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets Currently in Shortage
Anagrelide Hydrochloride Capsules Currently in Shortage
Asparaginase Erwinia Chrysanthemi (Erwinaze) Currently in Shortage
Atropine Sulfate Injection Currently in Shortage
Atropine Sulfate Ophthalmic Ointment Currently in Shortage
AVYCAZ® (ceftazidime and avibactam) for Injection, 2 grams/0.5 grams Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1% Resolved
Azithromycin Tablets Currently in Shortage
Bacitracin Ophthalmic Ointment Resolved
Belatacept (Nulojix) Lyophilized Powder for Injection Currently in Shortage
Bumetanide Injection, USP Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection, USP Currently in Shortage
Bupivacaine Hydrochloride Injection, USP Currently in Shortage
Buspirone HCl Tablets Resolved
Calcitriol Injection USP 1MCG /ML Currently in Shortage
Calcium Chloride Injection, USP Currently in Shortage
Capreomycin Injection, USP Currently in Shortage
Carbidopa and Levodopa Extended Release Tablets Resolved
Carisoprodol Tablets, USP Resolved
Cefazolin Injection Currently in Shortage
Cefepime Injection Currently in Shortage
Cefotaxime Sodium Injection Currently in Shortage
Cefotetan Disodium Injection Currently in Shortage
Cefoxitin for Injection, USP Currently in Shortage
Chloroquine Phosphate Tablets Resolved
Cisatracurium Besylate Injection Currently in Shortage
Continuous Renal Replacement Therapy (CRRT) Solutions Currently in Shortage
Cysteine Hydrochloride Injection Resolved
Deferoxamine Mesylate for Injection, USP Resolved
Dexamethasone Sodium Phosphate Injection Currently in Shortage
Dexmedetomidine Injection Currently in Shortage
Dexrazoxane Injection Resolved
Dextrose 25% Injection Currently in Shortage
Dextrose 5% Injection Bags Resolved
Dextrose 50% Injection Currently in Shortage
Diazepam Injection, USP Resolved
Dicyclomine Oral Tablets/Capsules Currently in Shortage
Difluprednate (Durezol) Ophthalmic Emulsion Resolved
Diltiazem Hydrochloride Currently in Shortage
Diltiazem Hydrochloride ER (Twice-a-Day) Capsules Resolved
Dimercaprol (Bal in Oil) Injection USP Currently in Shortage
Diphenhydramine Injection Currently in Shortage
Disulfiram Tablets Currently in Shortage
Dobutamine Hydrochloride Injection Currently in Shortage
Dopamine Hydrochloride Injection Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution Currently in Shortage
Dorzolamide Hydrochloride Ophthalmic Solution Currently in Shortage
Doxycycline Hyclate Injection Currently in Shortage
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution Currently in Shortage
Enalaprilat Injection, USP Currently in Shortage
Epinephrine Injection, 0.1 mg/mL Currently in Shortage
Epinephrine Injection, Auto-Injector Currently in Shortage
Erythromycin Lactobionate for Injection, USP Currently in Shortage
Erythromycin Ophthalmic Ointment Currently in Shortage
Ethiodized Oil (Lipiodol) Injection Resolved
Etomidate Injection Currently in Shortage
Famotidine Injection Currently in Shortage
Famotidine Tablets Currently in Shortage
Fentanyl Citrate (Sublimaze) Injection Currently in Shortage
Fludrocortisone Acetate Tablets Resolved
Fluorescein Injection Currently in Shortage
Fluorescein Sodium and Benoxinate Hydrochloride Ophthalmic Solution Resolved
Fluorescein Strips Currently in Shortage
Flurazepam Hydrochloride Capsules Currently in Shortage
Fluvoxamine ER Capsules Currently in Shortage
Furosemide Injection, USP Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets Currently in Shortage
Guanfacine Hydrochloride Tablets Currently in Shortage
Haloperidol Tablets Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection Currently in Shortage
Hydrocortisone Tablets, USP Currently in Shortage
Hydromorphone Hydrochloride Injection, USP Currently in Shortage
Hydroxychloroquine Sulfate Tablets Resolved
Hydroxyprogesterone Caproate Injection Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert Currently in Shortage
Hydroxyzine Pamoate Oral Capsules Currently in Shortage
Imipenem and Cilastatin for Injection, USP Currently in Shortage
Isocarboxazid Tablets Resolved
Ketamine Injection Currently in Shortage
Ketoprofen Capsules Currently in Shortage
Ketorolac Tromethamine Injection Currently in Shortage
Labetalol Hydrochloride Injection Currently in Shortage
Latanoprost Ophthalmic Solution 0.005% Resolved
Letermovir (Prevymis) Injection Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection Currently in Shortage
Leuprolide Acetate Injection Currently in Shortage
Levetiracetam Extended-Release Oral Tablets, USP Currently in Shortage
Levetiracetam Immediate-Release Oral Tablets, USP Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine Currently in Shortage
Lithium Oral Solution Currently in Shortage
Lorazepam Injection, USP Currently in Shortage
Loxapine Capsules Currently in Shortage
Methadone Hydrochloride Injection Currently in Shortage
Methocarbamol Tablets Resolved
Methotrexate Sodium Injection Resolved
Methyldopa Tablets Currently in Shortage
Methylphenidate Hydrochloride (QUILLICHEW ER) Extended-Release Chewable Tablets Resolved
Methylphenidate Hydrochloride (QUILLIVANT XR) for Extended-Release Oral Suspension Currently in Shortage
Metoclopramide Injection, USP Resolved
Metoprolol Tartrate Injection, USP Currently in Shortage
Metronidazole Injection, USP Currently in Shortage
Midazolam Injection, USP Currently in Shortage
Morphine Sulfate Injection, USP Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric) Currently in Shortage
Nalbuphine Hydrochloride Injection Currently in Shortage
Nelarabine (Arranon) Injection Resolved
Nizatidine Capsules Currently in Shortage
Nystatin Oral Suspension Resolved
Olmesartan Medoxomil Tablets Resolved
Ondansetron Hydrochloride Injection Currently in Shortage
Oxytocin Injection, USP Synthetic Currently in Shortage
Pantoprazole Sodium for Injection Currently in Shortage
Parathyroid Hormone (Natpara) Injection Currently in Shortage
Penicillamine (Depen) Titratable Tablets Resolved
Pentamidine Isethionate (Nebupent) For Inhalation Solution Resolved
Peritoneal Dialysis Solutions Resolved
Phenytoin Sodium Injection, USP Resolved
Physostigmine Salicylate Injection, USP Currently in Shortage
Pindolol Tablets Currently in Shortage
Piperacillin and Tazobactam (Zosyn) Injection Resolved
Potassium Acetate Injection, USP Currently in Shortage
Potassium Chloride Injection Resolved
Prednisolone Acetate 1% Ophthalmic Suspension Resolved
Primaquine Phosphate Tablet, EQ 15mg Base Resolved
Procainamide Hydrochloride Injection, USP Currently in Shortage
Progesterone Injection, USP Resolved
Promethazine (Phenergan) Injection Currently in Shortage
Propofol Injectable Emulsion Currently in Shortage
Remifentanil (Ultiva) Lyophilized Powder for Solution Injection Resolved
Rifapentine Tablets Currently in Shortage
Rocuronium Bromide Injection Resolved
Ropivacaine Hydrochloride Injection Currently in Shortage
Sclerosol Intrapleural Aerosol Currently in Shortage
Scopolamine Transdermal System Resolved
Sertraline Hydrochloride Oral Solution, USP Currently in Shortage
Sertraline Hydrochloride Tablets Currently in Shortage
Sildenafil Citrate (REVATIO) Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection Currently in Shortage
Sodium Acetate Injection, USP Currently in Shortage
Sodium Bicarbonate Injection, USP Currently in Shortage
Sodium Chloride 0.9% Injection Bags Resolved
Sodium Chloride 23.4% Injection Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes Currently in Shortage
Sodium Phosphate Injection Resolved
Sterile Water Resolved
Sulfasalazine Tablets Currently in Shortage
Tacrolimus Capsules Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA) Currently in Shortage
Thioridazine Hydrochloride Tablets Resolved
Thiothixene Capsules Currently in Shortage
Timolol Maleate Ophthalmic Gel Forming Solution Currently in Shortage
Timolol Maleate Ophthalmic Solution Currently in Shortage
Timolol Maleate Tablets Currently in Shortage
Triamcinolone Acetonide (Triesence) Injection, Suspension Currently in Shortage
Trifluoperazine Hydrochloride Tablets Resolved
Trifluridine Ophthalmic Solution Currently in Shortage
Valsartan Tablets Resolved
Vecuronium Bromide for Injection Currently in Shortage
Vinblastine Sulfate Injection Resolved
Vincristine Sulfate Injection, USP (Preservative-Free) Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abciximab (ReoPro) Injection
Abiraterone Acetate Tablets
Acarbose (Precose) Tablets
Acetaminophen/Tramadol Hydrochloride (Ultracet) Tablets
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Acyclovir Capsules, USP
Acyclovir Tablets, USP
Adalimumab (Humira) Pre-filled Syringe
Albuterol Sulfate and Ipratropium Bromide Inhalation Solution
Alfentanil Injection
Amantadine Hydrochloride Capsules
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amlodipine Besylate and Benazepril Hydrochloride Capsules
Amlodipine Besylate and Olmesartan Medoxomil Tablets
Amoxicillin Powder for Suspension
Anastrozole Tablets
Argatroban Injection
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Atracurium Besylate Injection, USP
Avelox® (moxifloxacin HCl) Tablets
Azacitidine Injection
Benzyl Alcohol (Ulesfia) Lotion 5%
Bethanechol Chloride Tablets
Betrixaban (Bevyxxa) Capsules
Bosentan Tablets
Budesonide Capsules
Buprenorphine Hydrochloride Sublingual Tablets
Bupropion Hydrochloride (Zyban) Tablets
Bupropion Hydrochloride Extended-Release Tablets
Busulfan Injection
Carbamazepine Extended Release Capsules
Carbidopa and Levodopa Extended Release Tablets
Carbinoxamine Maleate
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Carisoprodol Tablets, USP
Caspofungin Acetate Injection
Cefdinir Capsules
Cefepime Injection
Cefotetan Disodium Injection
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Cetirizine Hydrochloride
Chlordiazepoxide Hydrochloride USP, Capsules
Chlorothiazide Injection
Chlorothiazide Tablets
Chlorpheniramine Maleate; Hydrocodone Bitartrate; Pseudoephedrine Hydrochloride Oral Solution
Chlorpropamide Tablets
Ciprofloxacin Extended-Release Tablets
Clindamycin Injection, USP
Clindamycin Phosphate and Benzoyl Peroxide (Duac) Topical Gel
Clomiphene Citrate
Clonazepam Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Coumadin Tablets
Darifenacin Extended-release Tablets
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Deferasirox Tablets
Delavirdine Mesylate (RESCRIPTOR) Tablets
Demeclocycline Hydrochloride Tablets, USP
Desloratadine Tablets
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dexmedetomidine Injection
Dexmethylphenidate Hydrochloride Tablets
Dextroamphetamine Sulfate Extended-Release Capsules
Diclofenac Sodium Extended Release Tablets
Diclofenac Sodium Topical Gel
Diclofenac Sodium Topical Solution
Dicyclomine Hydrochloride (BENTYL®) Capsule & Tablet
Didanosine Delayed-Release Capsules USP
Diethylpropion Hydrochloride Controlled-Release Tablets
Diethylpropion Hydrochloride Tablets
Diltiazem Hydrochloride
Diltiazem Hydrochloride Extended-Release Capsules
Disulfiram Tablets
Divalproex Sodium Extended-Release Tablets
Dobutamine Hydrochloride Injection
Docetaxel Injection
Docusate Sodium Capsules, USP
Donepezil Hydrochloride Tablets
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxorubicin Hydrochloride Injection
Doxycycline Capsules
Doxycycline Hyclate Capsules
Doxycycline Hyclate Delayed Release Tablets
Dronabinol Capsules
Dutasteride Capsules
Enalaprilat Injection, USP
Entecavir Tablets
Epinastine Hydrochloride (Elestat®) Ophthalmic Solution
Epirubicin Hydrochloride Injection
Eprosartan Mesylate Tablets
Eptifibatide (Integrilin) Injection
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Escitalopram (Lexapro) 5 mg/5 mL Oral Solution
Ethinyl Estradiol and Levonorgestrel (Myzilra)
Ethinyl Estradiol; Norgestrel Tablets
Ethosuximide Oral Solution, USP
Etomidate (Amidate) Injection
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Ezetimibe Tablets
Fenofibric Acid Delayed-Release Capsules
Fentanyl (Duragesic 100, 12, 25, 37, 50, 75) Extended-Release Film
Finasteride Tablets
Fludarabine Phosphate for Injection, USP
Flumazenil Injection
Fluorouracil Injection
Fluoxetine Capsules
Fluphenazine Hydrochloride Tablets
Flurbiprofen Tablets
Flutamide Capsules, USP
Fluvastatin Sodium Extended-Release Tablets
Folic Acid Tablets, USP
Gadopentetate Dimeglumine (Magnevist) Injection
Gemcitabine Hydrochloride Injection
Glimepiride Tablets
Glipizide Tablets
Glycopyrrolate (Seebri Neohaler) Inhalation Powder
Guanfacine Hydrochloride Extended-Release Tablets
Hydrochlorothiazide (Microzide) Capsules
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocortisone Acetate Suppository
Hydrocortisone Tablets, USP
Hydromorphone Hydrochloride Extended-Release Tablets, CII
Ifosfamide/Mesna Kit
Indacterol Maleate (Arcapta Neohaler) Inhalation Powder
Indacterol Maleate and Glycopyrrolate (Utibron Neohaler) Inhalation Powder
Indinavir (CRIXIVAN) Capsules
Indomethacin Capsules
INTRON A (Interferon alfa-2b) Recombinant for Injection
Isosorbide Mononitrate Extended-Release Tablets, USP
Ketoconazole Tablets
Ketoprofen Capsules
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lamotrigine Tablets
Lanoxin (digoxin) Tablets
Lesinurad (ZURAMPIC) Tablets
Lesinurad/Allopurinol (DUZALLO®) Tablets
Levetiracetam Extended-Release Oral Tablets, USP
Levetiracetam Oral Tablets, USP
Levocetirizine Dihydrochloride Tablets
Levofloxacin Tablets
Levoleucovorin Calcium Injection
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril (Prinivil) Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Medroxyprogesterone Acetate (Provera) Tablet
Megestrol Acetate (Megace) Oral Suspension
Mesalamine (CANASA®) Suppositories
Mesna Injection
Metaproterenol Sulfate Tablets, USP
Metformin Hydrochloride Extended Release Tablets
Metformin Hydrochloride Tablets
Methocarbamol Tablet, USP
Methotrexate Sodium Injection
Methotrexate Tablets, USP
Methscopolamine Bromide Tablets
Methscopolamine Bromide, Tablets, USP
Methyclothiazide Tablets
Methyldopa Tablets
Methylphenidate Hydrochloride Extended-Release Tablets, USP CII
Methylphenidate Hydrochloride Tablets, USP CII
Methylprednisolone Tablets
Metoprolol Tartrate Tablets
Minocycline Hydrochloride Extended-Release Tablets, USP
Mirtazapine Orally Disintegrating Tablets
Mirtazapine Tablets, USP
Modafinil Tablets
Mometasone Furoate (Elocon) Topical Cream
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate and Naltrexone Hydrochloride (EMBEDA®) Extended-Release Capsules
Morphine Sulfate Extended-Release Tablets
Morphine Sulfate Injection, USP
Mupirocin Calcium Nasal Ointment
Mycophenolic Acid Delayed Release Tablets
Nafcillin Sodium Injection
Naftifine Hydrochloride Cream
Naratriptan Hydrochloride Tablets
Neomycin and Polymyxin B Sulfates Solution For Irrigation, USP
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Extended Release Tablets
Nifedipine Extended-Release Tablet, USP
Nizatidine Capsules
Norethindrone (NOR QD) Tablets
Norethindrone and Ethinyl Estradiol and Ferrous Fumarate Tablets
Nystatin Cream, USP
Ocriplasmin (Jetrea) Injection
Olanzapine and Fluoxetine (Symbyax) Capsules
Olaratumab (Lartruvo) Injection
Olmesartan Medoxomil and Hydrochlorothiazide Tablets
Olopatadine Hydrochloride (Pataday) Ophthalmic Solution
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Omega-3-Acid Ethyl Esters
Omeprazole Delayed-Release 40 mg Capsules
Oxybutynin Chloride Extended-Release Tablets
Oxycodone Hydrochloride Tablets
Oxymorphone Hydrochloride
Oxytocin (Pitocin) Synthetic Injection, USP
Paclitaxel Injection, USP
Peginterferon alfa-2b (Sylatron)
PEGINTRON (peginterferon alfa-2b) Injection
Penicillin V Potassium Tablets
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Pramipexole Dihydrochloride Extended Release Tablets
Primidone Tablets, USP
Prinivil Tablets
Promethazine Hydrochloride Injection, Solution
Promethazine Suppository
Pyrazinamide Tablets, USP
Quinapril Hydrochloride (Accupril) Tablets
Quinidine Gluconate Injection
Rabeprazole Sodium Delayed-Release Tablets
Ranitidine Injection, USP
Ranitidine Tablets/Capsules
Ranolazine Extended Release Tablets
Repaglinide Tablets
Ribavirin (Rebetol) Oral Solution
Ribavirin Capsules and Tablets
Rifampin (Rifadin) Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risedronate Sodium Tablets
Risedronate Tablets
Risperidone Tablets
Rivastigmine Tartrate Capsules
Rizatriptan Benzoate Orally Disintegrating Tablets
Ropinirole Hydrochloride Extended Release (Requip XL) Tablets
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Sodium Lactate Injection, USP
Somatropin Recombinant (Humatrope) Injection
Sotalol Hydrochloride Tablets
Spironolactone Tablets
Spironolactone Tablets, USP
Stavudine Capsules
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate (Imitrex) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Technetium Tc99m Succimer Injection (DMSA)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide (TEMODAR) Capsules
Temozolomide Capsules
Testosterone Buccal System
Testosterone Gel 1%
Testosterone Topical Gel
Tizanidine Hydrochloride Tablets
Tolazamide Tablets
Tolbutamide Tablets
Tolterodine Tartrate (Detrol LA) Extended Release Capsules
Tositumomab and Iodine I 131 Tositumomab (Bexxar)
Tramadol Hydrochloride (Ultram) Tablets
Trandolapril Tablets
Tranexamic Acid Tablets
Trazodone Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide (Dyazide) Capsules
Triamterene and Hydrochlorothiazide Tablets
Valacyclovir Hydrochloride Tablets
Valsartan Tablets
Vardenafil Hydrochloride (Levitra) Tablets
Verapamil HCl Extended-Release Tablets
Verapamil Hydrochloride Extended-Release Tablets and Capsules
Verapamil Hydrochloride Tablets
Vincristine Sulfate (VINCASAR PFS) Injection, USP
Vinorelbine Tartrate Injection
Zoledronic Acid Injection
Zolpidem Tartrate Extended Release Tablets
Zolpidem Tartrate Tablets







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