FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

A drug receives Resolved status when the Drug Shortages Staff (DSS) determines that the market is covered, based on information from all manufacturers. The market is considered covered when supply is available from at least one manufacturer to cover total market demand. However, some manufacturers may not have all presentations available. DSS monitors the supply of products with Resolved status. For the most current supply information, contact the manufacturers.

Generic Name or Active Ingredient Status
Acetazolamide Injection Currently in Shortage
Amifostine Injection Currently in Shortage
Amino Acids Currently in Shortage
Amoxapine Tablets Currently in Shortage
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets Currently in Shortage
Amphetamine Oral Suspension, Extended Release Currently in Shortage
Anagrelide Hydrochloride Capsules Resolved
Atropine Sulfate Injection Currently in Shortage
Azacitidine for Injection Currently in Shortage
Azithromycin (Azasite) Ophthalmic Solution 1% Currently in Shortage
Bacteriostatic 0.9% Sodium Chloride Injection Currently in Shortage
Bacteriostatic Water for Injection Currently in Shortage
Belatacept (Nulojix) Lyophilized Powder for Injection Currently in Shortage
Bumetanide Injection Currently in Shortage
Bupivacaine Hydrochloride and Epinephrine Injection Currently in Shortage
Bupivacaine Hydrochloride Injection Currently in Shortage
Calcium Disodium Versenate Injection Currently in Shortage
Calcium Gluconate Injection Currently in Shortage
Cefazolin Injection Currently in Shortage
Cefixime Oral Capsules Currently in Shortage
Cefotaxime Sodium Injection Currently in Shortage
Cefotetan Disodium Injection Currently in Shortage
Cefoxitin for Injection Resolved
Ceftazidime and Avibactam (AVYCAZ®) for Injection, 2 grams/0.5 grams Resolved
Ceftolozane and Tazobactam (Zerbaxa) Injection Resolved
Chlordiazepoxide Hydrochloride Capsules Currently in Shortage
Chloroprocaine Hydrochloride Injection Currently in Shortage
Cisatracurium Besylate Injection Resolved
Conivaptan Hydrochloride (Vaprisol) in 5% Dextrose Plastic Container Currently in Shortage
Continuous Renal Replacement Therapy (CRRT) Solutions Currently in Shortage
Cortisone Acetate Tablets Currently in Shortage
Cyclopentolate Ophthalmic Solution Currently in Shortage
Cysteamine Hydrochloride Ophthalmic Solution Currently in Shortage
Cysteine Hydrochloride Injection Resolved
Cytarabine Injection Currently in Shortage
Dacarbazine Injection Currently in Shortage
Deferoxamine Mesylate for Injection, USP Resolved
Desmopressin Acetate Nasal Spray Currently in Shortage
Dexamethasone Sodium Phosphate Injection Currently in Shortage
Dexmedetomidine Injection Currently in Shortage
Dextrose 10% Injection Currently in Shortage
Dextrose 25% Injection Currently in Shortage
Dextrose 5% Injection Currently in Shortage
Dextrose 50% Injection Currently in Shortage
Diflunisal Tablets Currently in Shortage
Difluprednate (Durezol) Ophthalmic Emulsion Resolved
Digoxin Injection Currently in Shortage
Diltiazem Hydrochloride Injection Currently in Shortage
Dimercaprol (Bal in Oil) Injection Resolved
Disopyramide Phosphate (Norpace) Capsules Currently in Shortage
Dobutamine Hydrochloride Injection Currently in Shortage
Dopamine Hydrochloride Injection Currently in Shortage
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution Resolved
Dorzolamide Hydrochloride Ophthalmic Solution Resolved
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution Currently in Shortage
Enalaprilat Injection Currently in Shortage
Epinephrine Injection, 0.1 mg/mL Currently in Shortage
Epinephrine Injection, Auto-Injector Currently in Shortage
Erythromycin Ophthalmic Ointment Resolved
Etomidate Injection Resolved
Famotidine Injection Resolved
Famotidine Tablets Resolved
Fentanyl Citrate (Sublimaze) Injection Currently in Shortage
Floxuridine for Injection Currently in Shortage
Fludarabine Phosphate Injection Currently in Shortage
Fludrocortisone Acetate Tablets Resolved
Fluorescein Injection Currently in Shortage
Fluorescein Strips Resolved
Fluvoxamine ER Capsules Currently in Shortage
Furosemide Injection Currently in Shortage
Gemifloxacin Mesylate (Factive) Tablets Currently in Shortage
Gentamicin Sulfate Injection Currently in Shortage
Guanfacine Hydrochloride Tablets Currently in Shortage
Haloperidol Tablets Resolved
Heparin Sodium and Sodium Chloride 0.9% Injection Currently in Shortage
Hydralazine Hydrochloride Injection Resolved
Hydrocortisone Tablets Currently in Shortage
Hydromorphone Hydrochloride Injection Currently in Shortage
Hydroxocobalamin Injection Resolved
Hydroxyprogesterone Caproate Injection Resolved
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert Currently in Shortage
Hydroxyzine Pamoate Oral Capsules Resolved
Ibutilide Fumarate Injection Currently in Shortage
Imipenem and Cilastatin for Injection Currently in Shortage
Iodixanol (Visipaque) Injection Currently in Shortage
Iohexol (Omnipaque) Injection Currently in Shortage
Isoniazid Injection Currently in Shortage
Ketamine Injection Currently in Shortage
Ketoprofen Capsules Currently in Shortage
Ketorolac Tromethamine Injection Currently in Shortage
Leucovorin Calcium Lyophilized Powder for Injection Currently in Shortage
Leuprolide Acetate Injection Currently in Shortage
Levetiracetam Extended-Release Oral Tablets, USP Resolved
Levetiracetam Immediate-Release Oral Tablets, USP Resolved
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection Currently in Shortage
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine Currently in Shortage
Lipid Injection Currently in Shortage
Lithium Oral Solution Currently in Shortage
Lorazepam Injection Currently in Shortage
Loxapine Capsules Currently in Shortage
Lutetium Lu 177 Dotatate (LUTATHERA) Injection Currently in Shortage
Mannitol Injection Currently in Shortage
Mepivacaine Hydrochloride Injection Currently in Shortage
Methadone Hydrochloride Injection Resolved
Methohexital Sodium (Brevital) Injection Resolved
Methyldopa Tablets Currently in Shortage
Methylprednisolone Acetate Injection Currently in Shortage
Metoclopramide Injection, USP Resolved
Metronidazole Injection Currently in Shortage
Midazolam Injection Currently in Shortage
Misoprostol Tablets Resolved
Morphine Sulfate Injection Currently in Shortage
Multi-Vitamin Infusion (Adult and Pediatric) Currently in Shortage
Nalbuphine Hydrochloride Injection Resolved
Nefazodone Hydrochloride Tablets Currently in Shortage
Nizatidine Capsules Currently in Shortage
Ondansetron Hydrochloride Injection Resolved
Oxytocin Injection (Synthetic) Resolved
Paclitaxel Injection (protein-bound particles) Currently in Shortage
Pantoprazole Sodium for Injection Currently in Shortage
Parathyroid Hormone (Natpara) Injection Currently in Shortage
Pentamidine Isethionate (Nebupent) For Inhalation Solution Resolved
Pentostatin Injection Currently in Shortage
Phenytoin Sodium Injection, USP Resolved
Physostigmine Salicylate Injection Currently in Shortage
Pindolol Tablets Resolved
Potassium Acetate Injection Currently in Shortage
Potassium Chloride Concentrate Injection Currently in Shortage
Prednisolone Acetate 1% Ophthalmic Suspension Resolved
Progesterone Injection, USP Resolved
Promethazine (Phenergan) Injection Currently in Shortage
Propofol Injectable Emulsion Currently in Shortage
Protamine Sulfate Injection Currently in Shortage
Rifampin Capsules Currently in Shortage
Rifampin Injection Currently in Shortage
Rifapentine Tablets Currently in Shortage
Rocuronium Bromide Injection Resolved
Ropivacaine Hydrochloride Injection Currently in Shortage
Sclerosol Intrapleural Aerosol Currently in Shortage
Scopolamine Transdermal System Resolved
Semaglutide (WEGOVY®) Injection Currently in Shortage
Sertraline Hydrochloride Oral Solution, USP Resolved
Sertraline Hydrochloride Tablets Resolved
Sildenafil Citrate (REVATIO) Resolved
Sincalide (Kinevac) Lyophilized Powder for Injection Currently in Shortage
Sodium Acetate Injection Currently in Shortage
Sodium Bicarbonate Injection Currently in Shortage
Sodium Chloride 0.9% Injection Bags Currently in Shortage
Sodium Chloride 14.6% Injection Currently in Shortage
Sodium Chloride 23.4% Injection Currently in Shortage
Sodium Chloride Injection USP, 0.9% Vials and Syringes Currently in Shortage
Sodium Phosphates Injection Currently in Shortage
Sterile Water for Injection Currently in Shortage
Streptozocin Powder for Injection Currently in Shortage
Succimer (Chemet) Capsules Resolved
Sufentanil Citrate Injection Currently in Shortage
Sulfasalazine Tablets Currently in Shortage
Tacrolimus Capsules Resolved
Technetium Tc 99m Sulfur Colloid Injection Resolved
Technetium TC-99M Mebrofenin Injection Currently in Shortage
Technetium Tc99m Succimer Injection (DMSA) Currently in Shortage
Teprotumumab-trbw Currently in Shortage
Thiothixene Capsules Currently in Shortage
Timolol Maleate Ophthalmic Solution Resolved
Tobramycin Lyophilized Powder for Injection Resolved
Tocilizumab Injection Resolved
Triamcinolone Acetonide Injectable Suspension Currently in Shortage
Triamcinolone Hexacetonide Injectable suspension Currently in Shortage
Trimethobenzamide Hydrochloride Capsules Currently in Shortage
Valproate Sodium Injection Currently in Shortage
Varenicline Tartrate (Chantix) Tablets Currently in Shortage
Vecuronium Bromide for Injection Currently in Shortage
Vitamin A Palmitate (Aquasol A) Injection Resolved
Zinc Acetate Capsules Resolved
Zolpidem Tartrate (Edluar) Sublingual Tablets Resolved

Discontinuations Listed by Generic Name or Active Ingredient

Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. These drugs include those that are life-supporting, life-sustaining or for use in the prevention or treatment of a debilitating disease or condition, including any such drug used in emergency medical care or during surgery. The discontinuations listed on the site reflect information received from manufacturers and are for informational purposes only.

Withdrawal notifications can be found here: https://www.federalregister.gov

Generic Name or Active Ingredient
Abiraterone Acetate Tablets
Acrivastine and Pseudoephedrine Hydrochloride Capsules
Adalimumab (Humira) Pre-filled Syringe
Albuterol Sulfate Aerosol, Metered
Aliskiren and Hydrochlorothiazide Tablets
Alprostadil Suppository
Aluminum Hydroxide and Magnesium Carbonate (Gaviscon Regular Strength)
Amantadine Hydrochloride Capsules
Ambrisentan Tablets
Amiodarone Tablets
Amitriptyline Hydrochloride Tablets
Amphetamine Aspartate; Amphetamine Sulfate; Dextroamphetamine Saccharate; Dextroamphetamine Sulfate Tablets
Ampicillin for Injection
Aspirin/Dipyridamole (Aggrenox) Extended Release Capsules
Bacitracin Ophthalmic Ointment
Benzonatate Capsules
Betamethasone Valerate Topical Foam
Budesonide Capsules
Busulfan Injection
Capreomycin Injection
Captopril Tablets
Captopril/Hydrochlorothiazide Tablets
Cardene IV (nicardipine hydrochloride) 0.2 mg/mL in 5% Dextrose
Caspofungin Acetate Injection
Cefdinir Capsules
Cefdinir Powder for Suspension
Ceftazidime (Fortaz) Injection
Cefuroxime Sodium (Zinacef) Injection
Chlordiazepoxide Hydrochloride USP, Capsules
Clindamycin and Benzoyl Peroxide Gel, 1%/5%
Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/5%
Clindamycin Phosphate Topical Solution 1%
Clobetasol Propionate Ointment 0.05%
Clobetasol Propionate Topical Foam
Clobetasol Propionate Topical Solution, 0.05%
Clonazepam Tablets
Clonidine Hydrochloride Extended Release Tablets
Clozapine (FazaClo® ) Orally Disintegrating Tablets
Cytotec (Misoprostol) Tablets
Daptomycin Injection
Darifenacin Hydrobromide Tablets
Dasabuvir Sodium; Ombitasvir; Paritaprevir; Ritonavir (Viekira XR) Tablets
Deferasirox Tablets
Desogestrel and Ethinyl Estradiol Tablets (ORTHO-CEPT)
Dextroamphetamine Sulfate Extended-Release Capsules
Diazepam Oral Solution (Concentrate)
Diclofenac Sodium Extended Release Tablets
Didanosine Delayed-Release Capsules USP
Diflorasone Diacetate Ointment, 0.05%
Diltiazem Hydrochloride Injection
Disulfiram Tablets
Dofetilide Capsules
Dorzolamide Hydrochloride and Timolol Maleate (Cosopt) Ophthalmic Solution
Dorzolamide Hydrochloride Ophthalmic Solution
Doxycycline Capsules
Doxycycline Hyclate Powder for Suspension
Efavirenz Tablets
Ergotamine Tartrate and Caffeine (Cafergot) Tablets
Esomeprazole Sodium for Injection
Ethambutol Hydrochloride Tablets
Exenatide (BYDUREON) Extended Release for Injectable Suspension
Febuxostat Tablets
Finasteride Tablets
Flumazenil Injection
Fluocinonide Gel 0.05%
Fluocinonide Ointment 0.05%
Fluocinonide Topical Solution
Fluorometholone Ophthalmic Ointment
Fluoxetine Capsules
Fosphenytoin Sodium Injection
Furosemide Oral Solution
Furosemide Oral Solution, 10 mg/mL
Gemcitabine Hydrochloride Injection
Gentamicin Sulfate and Prednisolone Acetate Ophthalmic Ointment
Glipizide Tablets
Histrelin Acetate Implant
Hydrochlorothiazide and Lisinopril Tablets
Hydrocodone Bitartrate and Homatropine Methylbromide Oral Solution
Hydrocortisone Acetate Suppository
Imipramine Tablets
Indomethacin Capsules
Iopamidol (Isovue) Injection
Ketoprofen Capsules
Lamivudine and Tenofovir Disoproxil Fumarate Tablets
Lamivudine and Zidovudine Tablets
Lamivudine Tablets
Lanoxin (digoxin) Tablets
Levoleucovorin Calcium Pentahydrate Injection
Levoleucovorin Injection
Lidocaine HCl Topical Jelly
Liothyronine Sodium Tablets
Lisinopril Tablets
Loxapine Capsules
Meclizine Hydrochloride Tablets
Megestrol Acetate Suspension
Meloxicam Tablets
Memantine Hydrochloride Extended-Release Capsules
Mesalamine (CANASA®) Suppositories
Metaxalone Tablets
Metformin Hydrochloride Extended Release Tablets
Methimazole Tablets
Methocarbamol Injection
Methyldopa Tablets
Methylprednisolone Tablets
Metoclopramide Tablets
Metoprolol Tartrate Tablets
Metronidazole (Flagyl) Tablets
Mirtazapine Orally Disintegrating Tablets
Mometasone Furoate Monohydrate Nasal Spray
Montelukast Sodium Chewable Tablet
Montelukast Sodium Tablets
Morphine Sulfate Extended-Release Tablets
Moxifloxacin (Moxeza) Ophthalmic Solution
Nafcillin Injection
Nafcillin Sodium Injection
Naratriptan Hydrochloride Tablets
Nedocromil Sodium Ophthalmic Solution
Nesiritide Powder (NATRECOR) for Injection
Nevirapine (Viramune) Tablets
Nevirapine Oral Suspension
Norethindrone (NOR QD) Tablets
Nystatin and Triamcinolone Acetonide Cream
Nystatin and Triamcinolone Acetonide Ointment
Olanzapine and Fluoxetine (Symbyax) Capsules
Ombitasvir; Paritaprevir; Ritonavir (Technivie) Tablets
Omeprazole and Sodium Bicarbonate Powder for Suspension
Ondansetron Hydrochloride Injection
Oxybutynin Chloride Syrup
Paclitaxel Injection, USP
Peginterferon alfa-2b (Sylatron)
Pentoxifylline Extended-Release Tablets
Phenobarbital Oral Solution
Pioglitazone Hydrochloride Tablets
Pioglitazone/Metformin HCl (ACTOPLUS MET®) Tablets
Piroxicam Capsules
Pramipexole Dihydrochloride Extended Release Tablets
Procardia Capsules
ProHance® (Gadoteridol) Injection
Promethazine Hydrochloride Injection, Solution
Propafenone Hydrochloride Tablets
Propofol Injectable Emulsion
Ranolazine Extended Release Tablets
Repaglinide Tablets
Rifampin (Rifadin) Capsules
Rifampin/Isoniazid (Rifamate) Capsules
Rifampin/Isoniazid/Pyrazinamide (Rifater) Tablets
Risedronate Sodium Tablets
Risedronate Tablets
Risperidone Tablets
Samarium SM 153 Lexidronam (Quadramet) Injection
Saquinavir Mesylate (Invirase) 200mg Capsules
Simeprevir Capsules
Simvastatin (Zocor) Tablets
Simvastatin Tablets
Somatropin Recombinant (Humatrope) Injection
Spironolactone Tablets
Stavudine Capsules
Sulfacetamide Sodium and Prednisolone Acetate Ophthalmic Ointment
Sumatriptan (Sumavel DosePro) Injection
Sumatriptan Succinate Injection
Talwin (Pentazocine Lactate Injection, USP, CIV)
Telmisartan and Amlodipine (Twynsta) Tablets
Temozolomide Capsules
Tipranavir Oral Solution
Tizanidine Hydrochloride Capsules
Tizanidine Hydrochloride Tablets
Trandolapril Tablets
Tranexamic Acid Tablets
Triamcinolone Acetonide Cream
Triamterene and Hydrochlorothiazide Tablets
Trimethobenzamide Hydrochloride Capsules
Umbrasilib Tosylate Tablets
Valproic Acid Oral Solution
Vancomycin Hydrochloride for Injection
Vibramycin Hyclate (Doxycycline Hyclate) for Suspension
Vinorelbine Tartrate Injection
Zafirlukast Oral Tablets

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