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FDA Drug Shortages

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Current and Resolved Drug Shortages and Discontinuations Reported to FDA

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Bupivacaine Hydrochloride Injection
Status: Currently in Shortage
»Date first posted: 02/20/2018
»Therapeutic Categories: Anesthesia

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Areva Pharmaceuticals, Inc. (Revised 05/04/2023)

Company Contact Information:
812-399-3599, Option # 1

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 59923-717-05) Available

Dear Health Care Provider Letter (hyperlink)

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 59923-719-10) Available

Dear Health Care Provider Letter (hyperlink)

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 59923-718-05) Available

Dear Health Care Provider Letter (hyperlink)

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 59923-720-10) Available

Dear Health Care Provider Letter (hyperlink)

Demand increase for the drug

Eugia Pharma Specialties LTD. (Revised 09/07/2023)

Company Contact Information:
888-238-7880

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Bupivacaine Hydrochloride Preservative Free, Injection, 2.5 mg/1 mL (NDC 55150-167-10) Available Demand increase for the drug
Bupivacaine Hydrochloride Preservative Free, Injection, 2.5 mg/1 mL (NDC 55150-168-30) Available Demand increase for the drug
Bupivacaine Hydrochloride Preservative Free, Injection, 5 mg/1 mL (NDC 55150-169-10) Currently on backorder - next shipment September 2023 Check wholesalers for inventory Demand increase for the drug
Bupivacaine Hydrochloride Preservative Free, Injection, 5 mg/1 mL (NDC 55150-170-30) Available Demand increase for the drug
Bupivacaine Hydrochloride Preservative Free, Injection, 7.5 mg/1 mL (NDC 55150-171-10) Available Demand increase for the drug
Bupivacaine Hydrochloride Preservative Free, Injection, 7.5 mg/1 mL (NDC 55150-172-30) Available Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 55150-249-50) Available Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 55150-250-50) Currently on backorder - next shipment TBD Check wholesalers for inventory Demand increase for the drug

Fresenius Kabi USA, LLC (Revised 09/01/2023)

Company Contact Information:
888-386-1300

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-465-57) Backordered. Next release June 2023. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-467-57) Backordered. Next release September 2023. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-17) Next release not available at this time. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-37) Next release not available at this time. Demand increase for the drug
Sensorcaine, Injection, 2.5 mg/1 mL (NDC 63323-464-31) Backordered. Next release date not available at this time. Demand increase for the drug
Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-17) Backordered. Next release not available at this time. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-37) Next release not available at this time. Demand increase for the drug
Sensorcaine, Injection, 5 mg/1 mL (NDC 63323-466-31) Backordered. Next release not available at this time. Demand increase for the drug
Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-17) Available Check wholesalers for inventory. Demand increase for the drug
Sensorcaine, Injection, 7.5 mg/1 mL (NDC 63323-472-37) Available Check wholesalers for inventory. Demand increase for the drug

Hospira, Inc. (Revised 09/11/2023)

Company Contact Information:
844-646-4398

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 0409-1159-01) Next Delivery: September 2023; Estimated Recovery: December 2023

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 0409-1159-02) Limited Supply Available. Next Delivery: September 2023; Estimated Recovery: March 2024 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 0409-1160-01) Next Delivery: March 2024; Estimated Recovery: December 2024

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 0409-1162-01) Next Delivery: September 2023; Estimated Recovery: December 2023 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 0409-1162-02) Next Delivery: October 2023; Estimated Recovery: March 2024

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 0409-1163-01) Next Delivery: January 2024; Estimated Recovery: June 2024 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 0409-1165-01) Limited Supply Available. Next Delivery: October 2023; Estimated Recovery: December 2023 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 0409-1165-02) Available

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 0409-3613-01) Depleted

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 2.5 mg/1 mL (NDC 0409-1559-10) Next Delivery: October 2023; Estimated Recovery: December 2023

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 2.5 mg/1 mL (NDC 0409-1559-30) Limited Supply Available. Next Delivery: October 2023; Estimated Recovery: December 2023

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 2.5 mg/1 mL (NDC 0409-1587-50) Available

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 5 mg/1 mL (NDC 0409-1560-10) Next Delivery: November 2023; Estimated Recovery: March 2024 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 5 mg/1 mL (NDC 0409-1560-29) Limited Supply Available. Next Delivery: January 2024; Estimated Recovery: June 2024

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 5 mg/1 mL (NDC 0409-1610-50) Limited Supply Available. Next Delivery: September 2023; Estimated Recovery: June 2024 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 7.5 mg/1 mL (NDC 0409-1582-10) Limited Supply Available. Next Delivery and Estimated Recovery: September 2023 Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug
Marcaine, Injection, 7.5 mg/1 mL (NDC 0409-1582-29) Available

Dear Customer Letter - Supply Update of Earlier Delivery Dates

Demand increase for the drug

Huons Co., Ltd (Revised 11/15/2022)

Company Contact Information:
+82-2-854-4700 or via email intbiz@huons.com

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Bupivacaine Hydrochloride, Injection, 7.5 mg/1 mL (NDC 73293-0002-2) Available

Kindos Pharmaceuticals Co. Ltd. (Revised 07/28/2023)

Company Contact Information:
844-824-8426

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Bupivacaine Hydrochloride, Injection, 2.5 mg/1 mL (NDC 71288-723-52) Available Meitheal Pharmaceuticals is distributor/labeler Demand increase for the drug
Bupivacaine Hydrochloride, Injection, 5 mg/1 mL (NDC 71288-726-52) Available Meitheal Pharmaceuticals is distributor/labeler Demand increase for the drug
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