FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

Start Over | Back to Previous Screen

Promethazine Hydrochloride Injection
Status: Currently in Shortage
»Date first posted: 11/21/2023
»Therapeutic Categories: Analgesia/Addiction; Gastroenterology; Pediatric; Pulmonary/Allergy

Expand all

Hikma Pharmaceuticals USA, Inc. (Revised 09/18/2026)

Company Contact Information:
800-631-2174

Presentation	Availability and Estimated Shortage Duration	Related Information	Shortage Reason (per FDASIA)
Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-0928-25)	Unavailable	Additional lots will be available in the October 2026 timeframe. Product will be made available as it is released.	Demand increase for the drug
Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-0929-25)	Limited Availability	Estimated recovery: TBD	Demand increase for the drug
Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 0641-1495-35)	Available	Limited availability	Demand increase for the drug
Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 0641-1496-35)	Available	Additional lots are scheduled to be manufactured. Product will be made available as it is released.
Phenergan, Injection, 25 mg/1 mL (NDC 0641-6084-25)	Unavailable	Estimated recovery: TBD	Other
Phenergan, Injection, 50 mg/1 mL (NDC 0641-6085-25)	Unavailable	Estimated recovery: TBD	Other
Phenergan, Injection, 25 mg/1 mL (NDC 0641-6082-25)	Unavailable	Additional lots are scheduled to be manufactured. Product will be made available as it is released.	Other
Phenergan, Injection, 50 mg/1 mL (NDC 0641-6083-25)	Unavailable	Additional lots are scheduled to be manufactured. Product will be made available as it is released.

XGen Pharmaceuticals DJB, Inc. (Reverified 09/22/2026)

Company Contact Information:
866-390-4411

Presentation	Availability and Estimated Shortage Duration	Related Information	Shortage Reason (per FDASIA)
Promethazine Hydrochloride, Injection, 25 mg/1 mL (NDC 39822-5525-3)	Available
Promethazine Hydrochloride, Injection, 50 mg/1 mL (NDC 39822-5550-6)	Unvailable	Estimated recovery: TBD	Demand increase for the drug