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U.S. Department of Health and Human Services

Substances Added to Food (formerly EAFUS)

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The Substances Added to Food inventory replaces what was previously known as Everything Added to Foods in the United States (EAFUS).

The Substances Added to Food inventory includes the following types of ingredients regulated by the U.S. Food and Drug Administration (FDA):

  • Food additives and color additives that are listed in FDA regulations (21 CFR Parts 172, 173 and Parts 73, 74 respectively), and flavoring substances evaluated by FEMA* and JECFA*.
  • Generally Recognized as Safe (“GRAS”) substances that are listed in FDA regulations (21 CFR Parts 182 and 184).
  • Substances approved for specific uses in foods prior to September 6, 1958, known as prior-sanctioned substances (21 CFR Part 181).
  • Substances formerly used:
    • Prohibited substances that are listed in FDA regulations (21 CFR Part 189) as prohibited from use in food (labeled as "PROHIBITED" or "PROHIBITED WITH EXCEPTIONS").
    • Delisted color additives in FDA regulations (21 CFR 81.10 and/or 81.30) (labeled as "DELISTED").
    • Some substances "no longer FEMA GRAS"

It is important to note that the inventory is only a partial list of food ingredients. Inclusion in this inventory of information from non-FDA entities does not indicate an FDA approval or evaluation of this use.

Users also have the option to search multiple food ingredient and packaging inventories at one time. This includes the following substances not listed in the Substances Added to Food inventory:

For more information, please refer to Food Ingredient and Packaging Inventories.


Search and display hints

  • Select the Substance name below to view the additional details about the substance.
  • To sort by a specific field, click on the column header for that field.
  • To browse the records, use the Show All, First/Previous/Next/Last, and Jump To options at the bottom of the data table.
  • To search for a specific term (or phrase or partial word), enter that term in the Search box and select Show Items to display only those records that contain the selected term.
  • The search results may include terms not shown on the results pages, but included in the full record descriptions. For example, a search for “gum Arabic” will find the substance “Acacia”.
  • The search results will return hits of records containing words that include the search term. For example, a search for the color red will return results that include terms such as reducing, ingredient, and denatured.
Search within these results
Records Found: 3973 Show All Page 1 of 80
CAS Reg. No.*
(or other ID)
Substance* Used for*
(Technical Effect)
21 CFR*
9000-01-5 ACACIA, GUM (ACACIA SENEGAL (L.) WILLD.) EMULSIFIER OR EMULSIFIER SALT,
FLAVOR ENHANCER,
FORMULATION AID,
PROCESSING AID,
PROPELLANT,
SOLVENT OR VEHICLE,
STABILIZER OR THICKENER,
SURFACE-ACTIVE AGENT,
TEXTURIZER
172.230
184.1330
879496-95-4 ACAI BERRY EXTRACT FLAVORING AGENT OR ADJUVANT
55589-62-3 ACESULFAME POTASSIUM NON-NUTRITIVE SWEETENER 172.800
105-57-7 ACETAL FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
75-07-0 ACETALDEHYDE FLAVORING AGENT OR ADJUVANT 177.2410
182.60
64577-91-9 ACETALDEHYDE, BUTYL PHENETHYL ACETAL FLAVORING AGENT OR ADJUVANT
63449-64-9 ACETALDEHYDE DI-CIS-3-HEXENYL ACETAL FLAVORING AGENT OR ADJUVANT
13002-09-0 ACETALDEHYDE DIISOAMYL ACETAL FLAVORING AGENT OR ADJUVANT
5669-09-0 ACETALDEHYDE DI-ISOBUTYLACETAL FLAVORING AGENT OR ADJUVANT
28069-74-1 ACETALDEHYDE ETHYL CIS-3-HEXENYL ACETAL FLAVORING AGENT OR ADJUVANT
6986-51-2 ACETALDEHYDE ETHYL ISOBUTYL ACETAL FLAVORING AGENT OR ADJUVANT
25334-93-4 (+/-)-ACETALDEHYDE ETHYL ISOPROPYL ACETAL FLAVORING AGENT OR ADJUVANT
233665-90-2 ACETALDEHYDE HEXYL ISOAMYL ACETAL FLAVORING AGENT OR ADJUVANT
202188-43-0 ACETALDEHYDE 1,3-OCTANEDIOL ACETAL FLAVORING AGENT OR ADJUVANT
7493-57-4 ACETALDEHYDE PHENETHYL PROPYL ACETAL FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
60-35-5 ACETAMIDE--NLFG FLAVORING AGENT OR ADJUVANT
100-06-1 ACETANISOLE FLAVORING AGENT OR ADJUVANT 172.515
64-19-7 ACETIC ACID ANTIMICROBIAL AGENT,
FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT,
PH CONTROL AGENT
73.85
172.814
173.370
184.1005
108-24-7 ACETIC ANHYDRIDE FLAVORING AGENT OR ADJUVANT 172.892
513-86-0 ACETOIN FLAVORING AGENT OR ADJUVANT 182.60
94089-23-3 ACETOIN PROPYLENEGLYCOL KETAL FLAVORING AGENT OR ADJUVANT
977164-02-5 ALPHA-ACETOLACTATE DECARBOXYLASE ENZYME PREPARATION FROM BACILLUS SUBTILIS RECOMBINANT ENZYME 173.115
28060-90-4 ACETOLEIN
67-64-1 ACETONE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT,
SOLVENT OR VEHICLE,
WASHING OR SURFACE REMOVAL AGENT
73.1
73.30
73.345
73.615
173.210
175.105
175.320
176.180
176.300
177.2600
1336-17-0 ACETONE PEROXIDES 172.802
98-86-2 ACETOPHENONE FLAVORING AGENT OR ADJUVANT,
SOLVENT OR VEHICLE
172.515
27177-85-1 ACETOSTEARIN
72541-09-4 6-ACETOXYDIHYDROTHEASPIRANE FLAVORING AGENT OR ADJUVANT
4166-20-5 4-ACETOXY-2,5-DIMETHYL-3(2H)-FURANONE FLAVORING AGENT OR ADJUVANT
1608-72-6 (+/-)-1-ACETOXY-1-ETHOXYETHANE FLAVORING AGENT OR ADJUVANT
3572-06-3 4-(P-ACETOXYPHENYL)-2-BUTANONE FLAVORING AGENT OR ADJUVANT
164524-93-0 5-ACETYL-2,3-DIHYDRO-1,4-THIAZINE FLAVORING AGENT OR ADJUVANT
22940-86-9 2-ACETYL-3,5-DIMETHYLFURAN FLAVORING AGENT OR ADJUVANT
10599-70-9 3-ACETYL-2,5-DIMETHYLFURAN FLAVORING AGENT OR ADJUVANT
36871-78-0 4-ACETYL-2,5-DIMETHYL-3(2H)-FURANONE FLAVORING AGENT OR ADJUVANT
977043-63-2 2-ACETYL-3, 5(OR 6)-DIMETHYLPYRAZINE, MIXTURE OF ISOMERS FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
32974-92-8 2-ACETYL-3-ETHYLPYRAZINE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
142896-11-5 2-ACETYL-4-ISOPROPENYLPYRIDINE FLAVORING AGENT OR ADJUVANT
142896-12-6 4-ACETYL-2-ISOPROPENYLPYRIDINE FLAVORING AGENT OR ADJUVANT
142896-09-1 2-ACETYL-4-ISOPROPYLPYRIDINE FLAVORING AGENT OR ADJUVANT
136954-25-1 3-ACETYLMERCAPTOHEXYL ACETATE FLAVORING AGENT OR ADJUVANT
65-82-7 N-ACETYL-L-METHIONINE NUTRIENT SUPPLEMENT 172.372
4906-24-5 ACETYL METHYL CARBINYL ACETATE FLAVORING AGENT OR ADJUVANT
1193-79-9 2-ACETYL-5-METHYLFURAN FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
23787-80-6 2-ACETYL-3-METHYLPYRAZINE FLAVORING AGENT OR ADJUVANT
67860-38-2 4-ACETYL-2-METHYLPYRIMIDINE FLAVORING AGENT OR ADJUVANT
13679-74-8 2-ACETYL-5-METHYLTHIOPHENE FLAVORING AGENT OR ADJUVANT
22047-25-2 ACETYLPYRAZINE FLAVORING AGENT OR ADJUVANT
1122-62-9 2-ACETYLPYRIDINE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
350-03-8 3-ACETYLPYRIDINE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT

Show All 

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*Definitions

  • CAS Reg. No. (or other ID): Chemical Abstract Service (CAS) Registry Number® for the substance or a numerical code assigned by CFSAN to those substances that do not have a CAS Registry Number (977nnn-nn-n series).
  • Substance: The name of the ingredient as recognized by CFSAN.
  • Used for (Technical Effect): The physical or technical effect(s) the substance has in or on food; see 21 CFR 170.3(o) for definitions.
  • 21 CFR: Title 21 of the Code of Federal Regulations.
  • FEMA: The trade association, Flavor and Extract Manufacturers Association (FEMA), has established expert panels that evaluate and make independent conclusions on the GRAS status of flavoring substances.
  • JECFA: The Joint Expert Committee on Food Additives (JECFA) is an international expert scientific committee that is administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO). See JECFA Specifications for Flavourings disclaimer icon
CAS Reg. No.*
(or other ID)
Substance* Used for*
(Technical Effect)
21 CFR*

679662  

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