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U.S. Department of Health and Human Services

Substances Added to Food (formerly EAFUS)

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The Substances Added to Food inventory replaces what was previously known as Everything Added to Foods in the United States (EAFUS).

The Substances Added to Food inventory includes the following types of ingredients regulated by the U.S. Food and Drug Administration (FDA):

  • Food additives and color additives that are listed in FDA regulations (21 CFR Parts 172, 173 and Parts 73, 74 respectively), and flavoring substances evaluated by FEMA* and JECFA*.
  • Generally Recognized as Safe (“GRAS”) substances that are listed in FDA regulations (21 CFR Parts 182 and 184).
  • Substances approved for specific uses in foods prior to September 6, 1958, known as prior-sanctioned substances (21 CFR Part 181).
  • Substances formerly used:
    • Prohibited substances that are listed in FDA regulations (21 CFR Part 189) as prohibited from use in food (labeled as "PROHIBITED" or "PROHIBITED WITH EXCEPTIONS").
    • Delisted color additives in FDA regulations (21 CFR 81.10 and/or 81.30) (labeled as "DELISTED").
    • Some substances "no longer FEMA GRAS"

It is important to note that the inventory is only a partial list of food ingredients. Inclusion in this inventory of information from non-FDA entities does not indicate an FDA approval or evaluation of this use.

Users also have the option to search multiple food ingredient and packaging inventories at one time. This includes the following substances not listed in the Substances Added to Food inventory:

For more information, please refer to Food Ingredient and Packaging Inventories.


Search and display hints

  • Select the Substance name below to view the additional details about the substance.
  • To sort by a specific field, click on the column header for that field.
  • To browse the records, use the Show All, First/Previous/Next/Last, and Jump To options at the bottom of the data table.
  • To search for a specific term (or phrase or partial word), enter that term in the Search box and select Show Items to display only those records that contain the selected term.
  • The search results may include terms not shown on the results pages, but included in the full record descriptions. For example, a search for “gum Arabic” will find the substance “Acacia”.
  • The search results will return hits of records containing words that include the search term. For example, a search for the color red will return results that include terms such as reducing, ingredient, and denatured.
Download Substances Added to Food <em>(formerly EAFUS)</em> data in Microsoft Excel web format Download data from this searchable database in Excel format. If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.
Search within these results
Records Found: 68 Show 50 records at a time
CAS Reg. No.*
(or other ID)
Substance* Used for*
(Technical Effect)
21 CFR*
7493-63-2 ALLYL ANTHRANILATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
150-13-0 P-AMINOBENZOIC ACID NUTRIENT SUPPLEMENT
2050-08-0 AMYL SALICYLATE
1335-08-6 ANISIC ACID FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
100-52-7 BENZALDEHYDE FLAVORING AGENT OR ADJUVANT 182.60
65-85-0 BENZOIC ACID ANTIMICROBIAL AGENT,
FLAVORING AGENT OR ADJUVANT,
PH CONTROL AGENT
175.300
177.1390
184.1021
579-93-1 N-BENZOYLANTHRANILIC ACID FLAVORING AGENT OR ADJUVANT
120-51-4 BENZYL BENZOATE FLAVORING AGENT OR ADJUVANT,
SOLVENT OR VEHICLE
172.515
175.105
118-58-1 BENZYL SALICYLATE FLAVORING AGENT OR ADJUVANT 172.515
7756-96-9 BUTYL ANTHRANILATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
94-26-8 BUTYL P-HYDROXYBENZOATE FLAVORING AGENT OR ADJUVANT 172.515
2052-14-4 BUTYL SALICYLATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
2090-05-3 CALCIUM BENZOATE ANTIMICROBIAL AGENT 178.2010
98-89-5 CYCLOHEXANECARBOXYLIC ACID FLAVORING AGENT OR ADJUVANT
7779-16-0 CYCLOHEXYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT 172.515
89-86-1 2,4-DIHYDROXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
99-50-3 3,4-DIHYDROXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
1166-52-5 DODECYL GALLATE ANTIOXIDANT
94-30-4 ETHYL P-ANISATE FLAVORING AGENT OR ADJUVANT 172.515
87-25-2 ETHYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT 172.515
93-89-0 ETHYL BENZOATE FLAVORING AGENT OR ADJUVANT 172.515
38446-21-8 ETHYL N-ETHYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
5444-75-7 2-ETHYLHEXYL BENZOATE FLAVORING AGENT OR ADJUVANT
35472-56-1 ETHYL N-METHYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
118-61-6 ETHYL SALICYLATE FLAVORING AGENT OR ADJUVANT 172.515
1085-12-7 HEPTYLPARABEN ANTIOXIDANT 172.145
6789-88-4 HEXYL BENZOATE FLAVORING AGENT OR ADJUVANT
99-06-9 3-HYDROXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
99-96-7 4-HYDROXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
87-20-7 ISOAMYL SALICYLATE FLAVORING AGENT OR ADJUVANT 172.515
7779-77-3 ISOBUTYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT 172.515
120-50-3 ISOBUTYL BENZOATE FLAVORING AGENT OR ADJUVANT 172.515
65505-24-0 ISOBUTYL N-METHYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
87-19-4 ISOBUTYL SALICYLATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
939-48-0 ISOPROPYL BENZOATE FLAVORING AGENT OR ADJUVANT 172.515
579-75-9 2-METHOXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
586-38-9 3-METHOXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
100-09-4 4-METHOXYBENZOIC ACID FLAVORING AGENT OR ADJUVANT
2719-08-6 METHYL N-ACETYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
121-98-2 METHYL ANISATE FLAVORING AGENT OR ADJUVANT 172.515
134-20-3 METHYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT,
SOLVENT OR VEHICLE
182.60
93-58-3 METHYL BENZOATE ANTIMICROBIAL AGENT,
FLAVORING AGENT OR ADJUVANT
172.515
5925-68-8 S-METHYL BENZOTHIOATE FLAVORING AGENT OR ADJUVANT
10072-05-6 METHYL N,N-DIMETHYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
41270-80-8 METHYL N-FORMYLANTHRANILATE FLAVORING AGENT OR ADJUVANT
99-76-3 METHYL P-HYDROXYBENZOATE ANTIMICROBIAL AGENT,
FLAVORING AGENT OR ADJUVANT
172.515
181.23
184.1490
606-45-1 METHYL O-METHOXYBENZOATE FLAVORING AGENT OR ADJUVANT 172.515
85-91-6 METHYL N-METHYLANTHRANILATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
119-36-8 METHYL SALICYLATE FLAVORING AGENT OR ADJUVANT 175.105
177.1010
1034-01-1 OCTYL GALLATE ANTIOXIDANT
133-18-6 PHENETHYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT 172.515
94-47-3 PHENETHYL BENZOATE FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT
172.515
87-22-9 PHENETHYL SALICYLATE FLAVORING AGENT OR ADJUVANT 172.515
118-55-8 PHENYL SALICYLATE ANTIOXIDANT,
STABILIZER OR THICKENER
177.1010
87-41-2 PHTHALIDE FLAVORING AGENT OR ADJUVANT
582-25-2 POTASSIUM BENZOATE ANTIMICROBIAL AGENT 177.1210
5205-11-8 PRENYL BENZOATE FLAVORING AGENT OR ADJUVANT
2315-68-6 PROPYL BENZOATE FLAVORING AGENT OR ADJUVANT 172.515
121-79-9 PROPYL GALLATE ANTIOXIDANT,
FLAVORING AGENT OR ADJUVANT
172.615
175.125
175.300
175.380
175.390
176.170
177.1010
177.1210
177.1350
181.24
184.1660
94-13-3 PROPYL P-HYDROXYBENZOATE ANTIMICROBIAL AGENT,
FLAVORING AGENT OR ADJUVANT
172.515
181.23
184.1670
81-07-2 SACCHARIN NON-NUTRITIVE SWEETENER 172.812
180.37
6381-91-5 SACCHARIN, CALCIUM SALT NON-NUTRITIVE SWEETENER 180.37
128-44-9 SACCHARIN, SODIUM SALT ANTIMICROBIAL AGENT,
FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT,
NON-NUTRITIVE SWEETENER,
SOLVENT OR VEHICLE
180.37
69-72-7 SALICYLIC ACID FLAVORING AGENT OR ADJUVANT 175.105
175.300
177.2600
532-32-1 SODIUM BENZOATE ANTIMICROBIAL AGENT,
ANTIOXIDANT,
COLOR OR COLORING ADJUNCT,
FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT,
FUMIGANT,
PH CONTROL AGENT,
SURFACE-ACTIVE AGENT
181.23
184.1733
17114-82-8 SODIUM (4-METHOXYBENZOYLOXY)ACETATE FLAVORING AGENT OR ADJUVANT
617-01-6 O-TOLYL SALICYLATE FLAVORING AGENT OR ADJUVANT
121-34-6 VANILLIC ACID FLAVORING AGENT OR ADJUVANT

*Definitions

  • CAS Reg. No. (or other ID): Chemical Abstract Service (CAS) Registry Number® for the substance or a numerical code assigned by CFSAN to those substances that do not have a CAS Registry Number (977nnn-nn-n series).
  • Substance: The name of the ingredient as recognized by CFSAN.
  • Used for (Technical Effect): The physical or technical effect(s) the substance has in or on food; see 21 CFR 170.3(o) for definitions.
  • 21 CFR: Title 21 of the Code of Federal Regulations.
  • FEMA No.: The trade association, Flavor and Extract Manufacturers Association (FEMA), has established expert panels to evaluate and make independent determinations on the GRAS status of flavoring substances. The FEMA number is provided here as a reference to FEMA’s GRAS assessments.
  • JECFA: The Joint Expert Committee on Food Additives (JECFA) is an international expert scientific committee that is administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO). See JECFA Specifications for Flavourings <>
CAS Reg. No.*
(or other ID)
Substance* Used for*
(Technical Effect)
21 CFR*

679661  

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