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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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J Clin Microbiol 2012 Dec;50(12):4123-7

Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli by whole genome sequencing.

Ju W, Cao G, Rump L, Strain E, Luo Y, Timme R, Allard M, Zhao S, Brown E, Meng J


Non-O157 Shiga toxin-producing Escherichia coli (STEC) are emerging foodborne pathogens causing life threatening diseases and foodborne outbreaks. A better understanding of their evolution provides a framework for developing tools to control food safety. We obtained 15 genomes of non-O157 STEC strains, including O26, O111 and O103. Phylogenetic trees revealed close relationship between O26:H11 and O111:H11 and a scattered distribution of O111. We hypothesize that STEC serotypes with same H antigens might share common ancestors.

Category: Journal Article
PubMed ID: #23052305 DOI: 10.1128/JCM.02262-12
Includes FDA Authors from Scientific Area(s): Food Animal and Veterinary
Entry Created: 2012-10-12 Entry Last Modified: 2012-12-22