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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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J Immunogenet 1982 Aug;9(4):277-80

Murine in vivo carrier-specific IgG memory to DNP-Ficoll: variation among inbred strains.

Shott CF, Merchant B


BALB/cAnN and C3H/HeN mice were primed and challenged with DNP-Ficoll, a thymic independent (TI-2) antigen. They developed significant carrier-specific IgG memory responses: DNP-pneumococcal polysaccharide or DNP-hemocyanin challenge did not elicit memory responses. NZB/B1NJ mice failed to develop this memory response. Genetically controlled events apparently regulate the phenotypic expression of this effect.

Category: Journal Article
PubMed ID: #6181174 DOI: 10.1111/j.1744-313X.1982.tb00983.x
Includes FDA Authors from Scientific Area(s): Biologics
Entry Created: 2012-12-09