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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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J Virol 2013 Aug;87(15):8792-7

Identification of recombination in the envelope gene of simian foamy virus serotype 2 isolated from Macaca cyclopis.

Galvin TA, Ahmed IA, Shahabuddin M, Bryan T, Khan AS


The full-length sequence of simian foamy virus serotype 2 (SFVmcy-2), isolated from a Taiwanese macaque, was determined. SFVmcy-2 was highly-related to SFV serotype 1 (SFVmcy-1), an isolate from the same species, except in the putative receptor binding domain (RBD) in env, which contained novel sequences related to SFV serotype 3 (SFVagm-3), isolated from an African green monkey. The results identify a potential region of neutralization in SFVs and demonstrate recombination between genetically divergent foamy viruses.

Category: Journal Article
PubMed ID: #23698303 DOI: 10.1128/JVI.03555-12
Includes FDA Authors from Scientific Area(s): Biologics
Entry Created: 2013-01-04 Entry Last Modified: 2013-09-21