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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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J Environ Sci Health C 2013;31(3):213-55

Phototoxicity of herbal plants and herbal products.

Fu PP, Xia Q, Zhao Y, Wang S, Yu H, Chiang HM


Plants are used by humans in daily life in many different ways, including as food, herbal medicines, and cosmetics. Unfortunately, many natural plants and their chemical constituents are photocytotoxic and photogenotoxic, and these phototoxic phytochemicals are widely present in many different plant families. To date, information concerning the phototoxicity and photogenotoxicity of many plants and their chemical constituents is limited. In this review, we discuss phototoxic plants and their major phototoxic constituents; routes of human exposure; phototoxicity of these plants and their constituents; general mechanisms of phototoxicity of plants and phototoxic components; and several representative phototoxic plants and their photoactive chemical constituents.

Category: Journal Article
PubMed ID: #24024520 DOI: 10.1080/10590501.2013.824206
Includes FDA Authors from Scientific Area(s): Toxicological Research
Entry Created: 2013-09-13