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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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Urol Oncol 2015 Mar;33(3):133-6

Regulation of biologic oncology products in the FDA's Center for Biologics Evaluation and Research.

Bross PF, Fan C, George B, Shannon K, Joshi BH, Puri RK


In the United States, cancer vaccines and immunotherapies, including cell and gene therapies and peptides and proteins used as therapeutic vaccines, are regulated by the Food and Drug Administration's Center for Biologics Evaluation and Research in the Office of Cellular, Tissue, and Gene Therapies (OCTGT). Center for Biologics Evaluation and Research has licensed two immunotherapy products for urologic indications: bacillus Calmette-Guerin for superficial bladder cancer and sipuleucel-T for advanced prostate cancer. OCTGT places a high priority on scientific and regulatory activities that promote the development of safe and effective cancer therapy products. OCTGT has published guidance documents and developed innovative tools that are designed to aid the rapid development of biologic products for patient use. The success of immunotherapeutic products for urologic malignancies stands as an example for ongoing and future therapeutic research and discovery.

Category: Journal Article
PubMed ID: #25441459 DOI: 10.1016/j.urolonc.2014.10.016
Includes FDA Authors from Scientific Area(s): Biologics
Entry Created: 2014-12-03 Entry Last Modified: 2019-10-06