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U.S. Department of Health and Human Services

Scientific Publications by FDA Staff

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mSphere 2019 Sep 25;4(5):e00520-19

Glycoconjugates: what it would take to master these well-known yet little-understood immunogens for vaccine development.

Avci F, Berti F, Dull P, Hennessey J, Pavliak V, Prasad AK, Vann W, Wacker M, Marcq O


Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic. The lack of fundamental understanding of factors controlling clinical efficacy of glycoconjugate vaccines is discussed while key parameters demanding focused and collaborative research are identified.

Category: Journal Article, Editorial
PubMed ID: #31554723 DOI: 10.1128/mSphere.00520-19
PubMed Central ID: #PMC6763769
Includes FDA Authors from Scientific Area(s): Biologics
Entry Created: 2019-11-17