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Title:
Pharmacokinetics of sulphamonomethoxine and sulphadimethoxine following oral administration to cultured rainbow trout (Oncorhynchus mykiss).
Authors:
Uno K, Aoki T, Ueno R (1993b)
Drug:
Sulfadimethoxine
Fish species:
Trout, rainbow
Date:
1993
t1/2-hr:
134
Sample:
blood, serum
Ave Weight (gm):
240
Ave Water temp (°C):
15
Water:
Freshwater
Dosage:
200 mg/kg sd
Route:
PO
Comments:
Sampled from caudal vein. Residue ug/g max 3d, 14.5, 0.5h=nd, 1h=nd, 3h=0.89, 6h=1.11, 9h=3.45, 12=2.27, 24h=12.9, 2d=7.14, 3d=14.5, 5d=1.4, 7d=0.28, 10d=0.22, 13d=0.12, 16d=1.68, 20d=nd, 24d=0.90 ug/g. Nd after 28d.
Metabolites:
N4-A-SDM
Citation:
Aquaculture 115:209-219
Dep-time:
36 days
Link:
http://dx.doi.org/10.1016/0044-8486(93)90137-N
Genus Species:
Oncorhynchus mykiss
Drug Class:
Antibiotic-Sulfa
t1/2-detail:
134 h
Wt gm-detail:
210-270 g
Water temp (°C)-detail:
15 C
Dosage-detail:
200 mg/kg sd
Method:
HPLC
Authors-red:
Uno K, Aoki T, Ueno R (1993b)
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