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Title:
Single-dose pharmacokinetic study of oxolinic acid and vetoquinol, an oxolinic ester, in Atlantic salmon (Salmo salar) held in seawater and in vitro antibacterial activity against Aeromonas salmonicida.
Authors:
Samuelsen OB, Ervik A, Pursell L, Smith P
Drug:
Oxolinic acid
Fish species:
Salmon, Atlantic
Date:
2000
t1/2-hr:
11
Sample:
liver
Ave Weight (gm):
450
Ave Water temp (°C):
10
Water:
Saltwater
Dosage:
40 mg/kg sd
Route:
PO
Comments:
Peak residue 12 h= 6.08, 48 h= 0.85, 96 h= 0.11 ug/g.
Citation:
Aquaculture 187:213-224
Link:
http://dx.doi.org/10.1016/S0044-8486(00)00315-X
Genus Species:
Salmo salar
Drug Class:
Antibiotic-Quinolone
t1/2-detail:
11+/-1 h
Wt gm-detail:
400-500 g
Water temp (°C)-detail:
10.0+/-0.5 C
Dosage-detail:
40 mg/kg sd
Method:
HPLC
Authors-red:
Samuelsen OB, Ervik A, Pursell L, Smith P
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