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Title:
Pharmacokinetics of oxytetracycline in black tiger shrimp, Penaeus monodon, and the effect of cooking on the residues.
Authors:
Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
Drug:
Oxytetracycline
Fish species:
Shrimp, giant tiger prawn (black tiger)
Date:
2006
t1/2-hr:
16
Sample:
blood, hemolymph
Ave Weight (gm):
23
Ave Water temp (°C):
30
Water:
Brackish
Dosage:
50 mg/kg sd
Route:
PO
Comments:
AUC= ug h/ml=459, MRT h=27.2, C max ug/ml=21.1, tmax 4h. Bioaval=35.6. Residues from graph ug/ml, wd 0.5d=11, 1d=8, 2d=5, 3d=1, 4d=0.2, 5d=0.08.
Protein binding:
49
Citation:
Aquaculture 254:24-31
Link:
http://dx.doi.org/10.1016/j.aquaculture.2005.10.031
Genus Species:
Penaeus monodon
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
16.4 h
Wt gm-detail:
22.9+/-4.9g
Water temp (°C)-detail:
29-30 C
Dosage-detail:
50 mg/kg sd
Method:
HPLC
Authors-red:
Uno K, Aoki T, Kleechaya W, Tanasomwang V, Ruangpan L.
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