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Title:
Bioavailability and absorption analysis of oxytetracycline orally administered to the standardized moulting farmed farmed Pacific white shrimps (Panaeus vannamei).
Authors:
Faroongsarng D, Chandumpai A, Chiayvareesajja S, Theapparat Y
Drug:
Oxytetracycline
Fish species:
Shrimp, whiteleg
Date:
2007
t1/2-hr:
92
Sample:
blood, hemolymph
Ave Weight (gm):
18
Ave Water temp (°C):
28
Water:
Saltwater
Dosage:
51.4 mg/kg sd8
Route:
PO
Comments:
Cmax = 43.52 ug/mlL at 7 hr. AUC term = 1110 ug h/mL, AUCinf = 1155 ug h/mL, Transit = 71.5, Bioavailability = 80.6 %. Reported values: Cl = 0.035 mL/hr, Vd = 4.63 mL/g. Salinity 20 ppt. *abstract states incorrect dose (50 ug/gm vs 50 ug/Kg). Compare with Chiayvareesajja et 2006.
Cl:
0.035 mL/hr
Vd:
4.63 L/kg
Citation:
Aquaculture 269:89-97
Link:
http://dx.doi.org/10.1016/j.aquaculture.2007.04.019
Genus Species:
Litopenaeus vannamei
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
91.9 +/- 51.5 h
Wt gm-detail:
14-22 g
Water temp (°C)-detail:
28 +/- 2 C
Dosage-detail:
51.4 ug/g
Method:
HPLC
Authors-red:
Faroongsarng D, Chandumpai A, Chiayvareesajja S, Theapparat Y
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