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Title:
Oxytetracycline (OTC) accumulation and elimination in hemolymph, muscle and hepatopancreas of white shirmp Litopenaeus vannamei following an OTC-feed therapeutic treatment.
Authors:
Gomez-Jimenez S, Espinosa-Plascencia A, Valenzuela-Villa F, Bermudez-Almada MDC
Drug:
Oxytetracycline
Fish species:
Shrimp, whiteleg
Date:
2008
Sample:
blood, hemolymph
Ave Weight (gm):
15
Ave Water temp (°C):
28.6
Water:
Saltwater
Dosage:
132 mg/kg 14d
Route:
PO
Comments:
Cmax = 18.79+/- 5.87 ug/ml. Cmax reached 8d post-exposure. OTC concentration decreased to 0.08 ug/g in all tissues after 8d of OTC withdrawal
Citation:
Aquaculture 274:24-29
Dep-time:
10d
Link:
http://dx.doi.org/10.1016/j.aquaculture.2007.11.017
Genus Species:
Litopenaeus vannamei
Drug Class:
Antibiotic-Tetracycline
Wt gm-detail:
14-16 g
Water temp (°C)-detail:
28.6 +/- 0.2C
Dosage-detail:
132 mg/kg for 14d
Method:
HPLC
Authors-red:
Gomez-Jimenez S, Espinosa-Plascencia A, Valenzuela-Villa F, Bermudez-Almada MDC
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