Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Piperonyl butoxide enhances the bioconcentration and photoinduced toxicity of fluoranthene and benzo[a]pyrene to larvae of the grass shrimp (Palaemonetes pugio)
Authors:
Weinstein JE, Garner TR
Drug:
Benzo [a] pyrene+Piperonyl butoxide
Fish species:
Shrimp, daggerblade grass
Date:
2008
Sample:
whole body
Ave Weight (gm):
0
Ave Water temp (°C):
22
Water:
Saltwater
Dosage:
0.125 mg/L 96h
Route:
BATH
Comments:
Same as results for [Piperonyl butoxide+benzo [a] pyrene]. Benzo [a] pyrine (BaP) concentrations of 0, 0.11, 0.24, 0.54, 1.10, and 1.90 ug/L were achieved for each dose of Piperonyl butoxide (PBO). LC50=0.5ug/L. LD50=601ng/g. PBO significantly increased the bioconcentration of BaP, but only in the three lowest BaP treatments. In the 1.10 and 1.90 ug/L treatments there were no differences in tissue residues. PBO significantly increased the photoinduced toxicity of BaP. Water salinity was 20 ppt.
Citation:
Aquatic Toxicology 87: 28-36
Link:
http://dx.doi.org/10.1016/j.aquatox.2008.01.002
Genus Species:
Palaemonetes pugio
Drug Class:
Insecticide - Piperonyl; butoxide
Water temp (°C)-detail:
~22
Dosage-detail:
Actual dose=0.127 ug/L
Method:
HPLC
Authors-red:
Weinstein JE, Garner TR
-
-