Quick Links: Skip to main page content
Skip to Search
Skip to Topics Menu
Skip to Common Links
U.S. Food & Drug Administration
Follow FDA
En Español
Search FDA
Home
Food
Drugs
Medical Devices
Radiation-Emitting Products
Vaccines, Blood & Biologics
Animal & Veterinary
Cosmetics
Tobacco Products
PhishPharm - Detail
FDA Home
PhishPharm
Detail
-
Please note:
JavaScript must be enabled for this application to work properly.
Check your settings
if you are unsure if your JavaScript is enabled.
Title:
Comparative toxicokinetics of explosive compounds in Sheepshead minnows.
Authors:
Lotufo GR, Lydy MJ
Drug:
Hexahydro-1,3,5-Trinitro-1,3,5-triazine (RDX),
Fish species:
Minnow, sheepshead
Date:
2005
t1/2-hr:
8
Sample:
whole body
Ave Water temp (°C):
23
Water:
Saltwater
Dosage:
8.5 mg/L up to 6 h
Route:
BATH
Comments:
Ku-uptake (ml/g/h) = 0.15, Ke=0.09/h, BCF=N/A mg/g. No trend between elimination rate ahdn hydrophobicity among the chemicals studied (RDX and HMX slower than TNT and its metabolites.
Citation:
Archives of Environmental Contamination and Toxiciology
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16059748&query_hl=3
Genus Species:
Cyprinodon variegatus variegatus
Drug Class:
Organic-Hydrocarbon
t1/2-detail:
7;9 h
Wt gm-detail:
12 wk juvenile
Water temp (°C)-detail:
23 C
Dosage-detail:
8.5 mg/L up to 6 h
Method:
HPLC
Authors-red:
Lotufo GR, Lydy MJ
-
-