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PhishPharm - Detail
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Title:
Relative roles of metabolism and renal excretory mechanisms in xenobiotic elimination by fish.
Authors:
Pritchard JB, Bend JR
Drug:
BAP-(Benzo-a-pyrene)
Fish species:
Flounder, southern
Date:
1991
Sample:
urine
Ave Weight (gm):
1750
Ave Water temp (°C):
23
Water:
Saltwater
Dosage:
2.5 umol/kg
Route:
IV/IM
Comments:
Comparison of dose on urine concentration - low dose 0.25 umole/kg was 11.1 uM vs10.8 for 2.5 dose.
Cl:
10.4 ml/h vs 1.1 of hi dose
Citation:
Environmental Health Perspectives 90:85-92
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2050085
Genus Species:
Paralichthys lethostigma
Drug Class:
Organic-Hydrocarbon
Wt gm-detail:
500-3000 g
Water temp (°C)-detail:
22-24 C
Dosage-detail:
2.5 umol/kg
Method:
HPLC
Authors-red:
Pritchard JB, Bend JR
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