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Title:
Methyl mercury toxicokinetics in channel catfish (Ictalurus punctatus) and largemouth bass (Micropterus salmoides) after intravascular administration.
Authors:
Schultz IR, Newman MC
Drug:
Methylmercury
Fish species:
Catfish, channel
Date:
1997
t1/2-hr:
1670
Sample:
blood, plasma
Ave Weight (gm):
755
Ave Water temp (°C):
21
Water:
Freshwater
Dosage:
0.47 mg/kg sd
Route:
IV
Comments:
Salinity at 1ppt. Fish received a 2-h treatment in a 0.25 mg/L solution of malachite green. Fish anesthetized with 150 ml/L MS-222. AUC=23,300 ng/ml*h, Cmax=624 ng/ml, Mean Residence Time=1,829h.
Protein binding:
0.0364
Cl:
0.0260 ml/h/g
Vd:
30 ml/g
Citation:
Environmental Toxicology and Chemistry 16:990-996
Link:
http://dx.doi.org/10.1002/etc.5620160518
Genus Species:
Ictalurus punctatus
Drug Class:
Metal-Mercury
t1/2-detail:
1670+/-683
Wt gm-detail:
755+/-80g
Water temp (°C)-detail:
20-22C
Dosage-detail:
0.47 mg/kg sd
Method:
AAS
Authors-red:
Schultz IR, Newman MC
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