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Title:
Bioconcentration and elimination of avermectin B1 in sturgeon.
Authors:
Shen J, Zhang Q, Ding S, Zhang S, Coats JR
Drug:
Avermectin B1
Fish species:
Sturgeon
Date:
2005
t1/2-hr:
119
Sample:
muscle
Ave Weight (gm):
36
Ave Water temp (°C):
20
Water:
Freshwater
Dosage:
0.2 ng/ml 22d
Route:
BATH
Comments:
Residue 7.75 +/- 0.88ng/g d22..Withdrawal d 18=1.91 +/-0.37 ng/g. d40=ND The estimated value of bioconcentration factor was 42 L/kg, utake constant=5.9, elim constant =0.14, Average recoveries of fortified water samples were 80.5% +/- 5.1% for 1 ng/mL, 83.7% +/- 3.8% for 4 ng/mL, and 89.1 +/- 4.0% for 7 ng/mL.
Citation:
Environmental Toxicology and Chemistry 24: 396-399
Link:
http://www.ncbi.nlm.nih.gov/pubmed/15720000?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
Genus Species:
Acipenser sp
Drug Class:
Antiparasitic-Avermectin
t1/2-detail:
119 h
Wt gm-detail:
35.8+/-4.6g
Water temp (°C)-detail:
20+/-1 C
Dosage-detail:
Flow through 0.2 ng/ml for 22 days.
Method:
HPLC
Authors-red:
Shen J, Zhang Q, Ding S, Zhang S, Coats JR
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