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Title:
Comparative pharmacokinetics and bioavailability of oxytetracycline in giant tiger prawn.
Authors:
Sangrungruang K, Chotchuang A, Ueno R
Drug:
Oxytetracycline
Fish species:
Shrimp, giant tiger prawn (black tiger)
Date:
2004
t1/2-hr:
7
Sample:
blood, hemolymph
Ave Weight (gm):
24
Ave Water temp (°C):
30
Water:
Saltwater
Dosage:
10 mg/kg sd
Route:
PO
Comments:
Ka = 0.138 per hour, Ke = 0.1 per hour, Ta1/2 = 4.08 h, AUC = 455 ug/h/mL, MRT = 20 h. Tmax 9 hr. Bioavail 59.9%.
Vd:
14.3 L/kg
Citation:
Fisheries Science 70:467-472
Link:
http://dx.doi.org/10.1111/j.1444-2906.2004.00827.x
Genus Species:
Penaeus monodon
Drug Class:
Antibiotic-Tetracycline
t1/2-detail:
6.93 h
Wt gm-detail:
23.6 g
Water temp (°C)-detail:
30 C
Dosage-detail:
10 mg/kg sd
Method:
HPLC
Authors-red:
Sangrungruang K, Chotchuang A, Ueno R
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