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Title:
Residues of MS-222, benzocaine and their metabolites in striped bass following anesthesia.
Authors:
Luhning CW
Drug:
MS-222
Fish species:
Bass, striped
Date:
1973
t1/2-hr:
1
est:
est
Sample:
whole body-minus head, scales, viscera, fins
Ave Weight (gm):
68
Ave Water temp (°C):
19
Water:
Freshwater
Dosage:
100 mg/l 30 min
Route:
BATH
Comments:
Tricaine methane sulphonate, t1/2 est. from chart. Mean residues (ug/ g) free ms-222 residues at withdrawal time 0 h = 22.1, 15 min = 13.2, 30 min = 12.3, 45 min=7.8, 60 min = 5.6, m-aminobenzoic acid residue at withdrawal time 0 h = 19.4, 15 min 17.8,30 min=11.6, 45 min=11.6, 60 min = 94. MS222- N-acetyl derivative 0 h= 0.0, 15 min = 0.0, 30 min = 0.0, 45 min=0.5, 60 min = 0.0, m-aminobenzoic acid-N-acetyl derviative residue 0h=3.1, 15 min=2.2, 30 min = 2.0, 45 min=1.5, 60 min=1.6. Levels dropped significantly after storage of samples for 1 week at 1.7 C.
Metabolites:
m-aminobenzoic acid and acetylated metabolites
Citation:
Investigations in Fish Control. U.S. Dept. of the Interior, Fish and Wildlife Service, Bureau of Sport Fisheries and Wildlife. SH157.7.I58 no.52
Link:
none
Genus Species:
Morone saxatilis
Drug Class:
Anesthetic-Tricaine
t1/2-detail:
<1 h
Wt gm-detail:
67.6 g
Water temp (°C)-detail:
18 +/- 0.5 C
Dosage-detail:
100 mg/l 30 min
Method:
Absorbance-Bratton&Marshall, TLC
Authors-red:
Luhning CW
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