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Title:
Pharmacokinetic modeling of the dogfish shark (Squalus acanthias): Distribution and urinary and biliary excretion of phenol red and its glucuronide.
Authors:
Bungay PM, Dedrick RL, Guarino AM
Drug:
Phenol red
Fish species:
Shark, picked dogfish
Date:
1976
t1/2-hr:
12
est:
est
Sample:
liver
Ave Weight (gm):
5000
Ave Water temp (°C):
0
Water:
Saltwater
Dosage:
10 mg/kg sd
Route:
IV
Comments:
No metabolites found. T 1/2 est from graph.
Cl:
0.0312 L/kg/h
Citation:
J. Pharmacokinetics and Biopharmaceutics 4:5:377-388.
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1003326
Genus Species:
Squalus acanthias
Drug Class:
Organic-Phenol
t1/2-detail:
12 h est
Wt gm-detail:
3000-7000 g
Water temp (°C)-detail:
Not specified
Dosage-detail:
10 mg/kg sd
Method:
Absorbance
Authors-red:
Bungay PM, Dedrick RL, Guarino AM
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