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Title:
Furazolidone disposition after intravascular and oral dosing in the channel catfish.
Authors:
Plakas SM, El Said KR, Stehly GR
Drug:
Furazolidone
Fish species:
Catfish, channel
Date:
1994
t1/2-hr:
24
est:
est
Sample:
blood, plasma
Ave Weight (gm):
680
Ave Water temp (°C):
24
Water:
Freshwater
Dosage:
1 mg/kg sd
Route:
PO
Comments:
Furazolidone (14C) in solution. Concentrations of parent Furazolidone highest at 1 h and were below the limit of determination at 5 h. Residue of total radioactivity (ng/g) 2h = 588, 8 h=439, 24 h = 212, 96 h=124, 168 h=52. t 1/2 est from table.
Protein binding:
47% at 2 hr, 61% at 168 h
Citation:
Xenobiotica 24:11:1095-1105
Link:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7701851
Genus Species:
Ictalurus punctatus
Drug Class:
Antibiotic-Furan
t1/2-detail:
<24 h est
Wt gm-detail:
680+/-140 g
Water temp (°C)-detail:
24 C
Dosage-detail:
1 mg/kg sd
Method:
Rad
Authors-red:
Plakas SM, El Said KR, Stehly GR
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