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                     <code code="42229-5" codeSystem="2.16.840.1.113883.6.1" displayName="SPL UNCLASSIFIED SECTION"/>
                     <title>Allergy alert:</title>
                     <text>
                        <list listType="unordered">
                           <item>
                              <caption>•</caption>Do not use if you are allergic to esomeprazole</item>
                           <item>
                              <caption>•</caption>Esomeprazole may cause severe skin reactions. Symptoms include:</item>
                           <item>
                              <caption>•</caption>skin reddening</item>
                           <item>
                              <caption>•</caption>blisters</item>
                           <item>
                              <caption>•</caption>rash</item>
                        </list>
                        <paragraph>If an allergic reaction occurs, stop use and seek medical attention right away.</paragraph>
                     </text>
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                     <code code="50570-1" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - DO NOT USE SECTION"/>
                     <title>Do not use if you have</title>
                     <text>
                        <list listType="unordered">
                           <item>
                              <caption>•</caption>trouble or pain swallowing food, vomiting with blood, or bloody or black stools</item>
                           <item>
                              <caption>•</caption>heartburn with <content styleCode="bold">lightheadedness, sweating or dizziness</content>
                           </item>
                           <item>
                              <caption>•</caption>chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness</item>
                           <item>
                              <caption>•</caption>frequent <content styleCode="bold">chest pain</content>
                           </item>
                        </list>
                        <paragraph>These may be signs of a serious condition. See your doctor.</paragraph>
                     </text>
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                     <code code="50569-3" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - ASK DOCTOR SECTION"/>
                     <title>Ask a doctor before use if you have</title>
                     <text>
                        <list listType="unordered">
                           <item>
                              <caption>•</caption>had heartburn over 3 months. This may be a sign of a more serious condition.</item>
                           <item>
                              <caption>•</caption>frequent wheezing, particularly with heartburn</item>
                           <item>
                              <caption>•</caption>unexplained weight loss</item>
                           <item>
                              <caption>•</caption>nausea or vomiting</item>
                           <item>
                              <caption>•</caption>stomach pain</item>
                        </list>
                     </text>
                     <effectiveTime value="20210311"/>
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                     <code code="50568-5" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - ASK DOCTOR/PHARMACIST SECTION"/>
                     <text>
                        <list listType="ordered">
                           <item>
                              <caption> </caption>
                              <content styleCode="bold">Ask a doctor or pharmacist before use if you are</content>
                           </item>
                           <item>
                              <caption>•</caption>taking a prescription drug. Acid reducers may interact with certain prescription drugs. </item>
                        </list>
                     </text>
                     <effectiveTime value="20220609"/>
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                     <code code="50566-9" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - STOP USE SECTION"/>
                     <title>Stop use and ask a doctor if</title>
                     <text>
                        <list listType="unordered">
                           <item>
                              <caption>•</caption>your heartburn continues or worsens</item>
                           <item>
                              <caption>•</caption>you need to take this product for more than 14 days</item>
                           <item>
                              <caption>•</caption>you need to take more than 1 course of treatment every 4 months</item>
                           <item>
                              <caption>•</caption>you get diarrhea</item>
                           <item>
                              <caption>•</caption>you develop a rash or joint pain</item>
                        </list>
                     </text>
                     <effectiveTime value="20210311"/>
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                     <code code="53414-9" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - PREGNANCY OR BREAST FEEDING SECTION"/>
                     <text>
                        <paragraph>
                           <content styleCode="bold">If pregnant or breast-feeding,</content> ask a health professional before use.</paragraph>
                     </text>
                     <effectiveTime value="20210311"/>
                  </section>
               </component>
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                     <code code="50565-1" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - KEEP OUT OF REACH OF CHILDREN SECTION"/>
                     <text>
                        <paragraph>
                           <content styleCode="bold">Keep out of reach of children.</content> In case of overdose, get medical help or contact a Poison Control Center right away.</paragraph>
                     </text>
                     <effectiveTime value="20210311"/>
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            </section>
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               <text>
                  <paragraph>
                     <content styleCode="bold">
                        <content styleCode="italics">Directions</content>
                     </content>
                  </paragraph>
                  <list listType="unordered">
                     <item>
                        <caption>•</caption>adults 18 years of age and older</item>
                     <item>
                        <caption>•</caption>this product is to be used once a day (every 24 hours), every day for 14 days</item>
                     <item>
                        <caption>•</caption>may take 1 to 4 days for full effect<br/>
                        <content styleCode="bold">14-Day Course of Treatment Repeated 14-Day Courses (if needed)</content>
                        <list listType="unordered">
                           <item>
                              <caption>•</caption>swallow 1 capsule with a glass of water before eating in the morning</item>
                           <item>
                              <caption>•</caption>take every day for 14 days</item>
                           <item>
                              <caption>•</caption>do not take more than 1 capsule a day</item>
                           <item>
                              <caption>•</caption>swallow whole. Do not crush or chew capsules.</item>
                           <item>
                              <caption>•</caption>do not use for more than 14 days unless directed by your doctor</item>
                           <item>
                              <caption>•</caption>you may repeat a 14-day course every 4 months</item>
                           <item>
                              <caption>•</caption>
                              <content styleCode="bold">do not take for more than 14 days or more often than every 4 months unless directed by a doctor</content>
                           </item>
                        </list>
                     </item>
                     <item>
                        <caption>•</caption>children under 18 years of age: ask a doctor before use. Heartburn in children may sometimes be caused by a serious condition.</item>
                  </list>
               </text>
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               <text>
                  <paragraph>
                     <content styleCode="bold">
                        <content styleCode="italics">Other Information</content>
                     </content>
                  </paragraph>
                  <list listType="unordered">
                     <item>
                        <caption>•</caption>read the directions and warnings before use</item>
                     <item>
                        <caption>•</caption>keep the carton. It contains important information.</item>
                     <item>
                        <caption>•</caption>store at 20-25°C (68-77°F)</item>
                  </list>
               </text>
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               <code code="51727-6" codeSystem="2.16.840.1.113883.6.1" displayName="INACTIVE INGREDIENT SECTION"/>
               <text>
                  <paragraph>
                     <content styleCode="bold">
                        <content styleCode="italics">Inactive Ingredients (Nexium 24HR Capsules)</content>
                     </content>
                  </paragraph>
                  <paragraph>corn starch, D&amp;C red no. 28, FD&amp;C blue no. 1, FD&amp;C red no. 40, ferric oxide, gelatin, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer, pharmaceutical ink, polysorbate 80, sucrose, talc, titanium dioxide, triethyl citrate</paragraph>
                  <paragraph>
                     <content styleCode="bold">
                        <content styleCode="italics">Inactive Ingredients (Nexium 24HR ClearMinis)</content>
                     </content>
                  </paragraph>
                  <paragraph>carmine, corn starch, FD&amp;C blue no. 2, FD&amp;C blue no. 2 aluminum lake, FD&amp;C red no. 3, FD&amp;C red no. 40, ferric oxide, gelatin, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer, pharmaceutical ink, polysorbate 80, sucrose, talc, titanium dioxide, triethyl citrate</paragraph>
               </text>
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               <code code="53413-1" codeSystem="2.16.840.1.113883.6.1" displayName="OTC - QUESTIONS SECTION"/>
               <text>
                  <paragraph>
                     <content styleCode="bold">
                        <content styleCode="italics">Questions or comments?</content>
                     </content>
                  </paragraph>
                  <paragraph>call toll-free weekdays 9 AM to 5 PM EST at<content styleCode="bold"> 1-866-226-1600</content>
                  </paragraph>
               </text>
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               <code code="42229-5" codeSystem="2.16.840.1.113883.6.1" displayName="SPL UNCLASSIFIED SECTION"/>
               <title>Additional Information </title>
               <text>
                  <paragraph>
                     <content styleCode="bold">KEEP CARTON FOR COMPLETE WARNINGS AND IMPORTANT INFORMATION.</content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">Do Not Use if seal under bottle cap imprinted with <content styleCode="italics">“SEALED for YOUR PROTECTION”</content>
                     </content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">or yellow band around the center of each capsule is broken or missing.</content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">Tips for Managing Heartburn</content>
                  </paragraph>
                  <list listType="unordered">
                     <item>
                        <caption>•</caption>Avoid foods or drinks that are more likely to cause heartburn, such as rich, spicy, fatty and fried foods, chocolate, caffeine, alcohol and even some acidic fruits and vegetables.</item>
                     <item>
                        <caption>•</caption>Eat slowly and do not eat big meals.</item>
                     <item>
                        <caption>•</caption>Do not eat late at night or just before bedtime.</item>
                     <item>
                        <caption>•</caption>Do not lie flat or bend over soon after eating.</item>
                     <item>
                        <caption>•</caption>Raise the head of your bed.</item>
                     <item>
                        <caption>•</caption>Wear loose-fitting clothing around your stomach.</item>
                     <item>
                        <caption>•</caption>If you are overweight, lose weight.</item>
                     <item>
                        <caption>•</caption>If you smoke, quit smoking.</item>
                  </list>
                  <paragraph>Distributed by: GSK Consumer Healthcare,</paragraph>
                  <paragraph>Warren, NJ 07059</paragraph>
                  <paragraph>©2022 GSK group of companies or its licensor</paragraph>
                  <paragraph>Made in France</paragraph>
                  <paragraph>For most recent product information, visit www.Nexium24HR.com</paragraph>
                  <paragraph>Nexium is a registered trademark of AstraZeneca AB and is used under license.</paragraph>
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               <title>PRINCIPAL DISPLAY PANEL</title>
               <text>
                  <paragraph>
                     <content styleCode="bold">NDC 0573-2450-14</content>
                  </paragraph>
                  <paragraph>See new warning information</paragraph>
                  <paragraph>
                     <content styleCode="bold">Treats Frequent Heartburn</content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">Nexium<sup>®</sup>
                     </content>
                     <br/>
                     <content styleCode="bold">24HR</content>
                     <br/>esomeprazole magnesium<br/>delayed-release capsules<br/>20 mg/acid reducer</paragraph>
                  <paragraph>
                     <content styleCode="bold">Capsules</content>
                  </paragraph>
                  <paragraph>May take 1 to 4 days for full effect</paragraph>
                  <paragraph>
                     <content styleCode="bold">14</content>
                     <br/>
                     <content styleCode="bold">CAPSULES</content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">One 14-day course of treatment</content>
                  </paragraph>
                  <paragraph>000078381 Front Carton</paragraph>
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               <code code="51945-4" codeSystem="2.16.840.1.113883.6.1" displayName="PACKAGE LABEL.PRINCIPAL DISPLAY PANEL"/>
               <title>PRINCIPAL DISPLAY PANEL</title>
               <text>
                  <paragraph>
                     <content styleCode="bold">NDC 0573-2452-14</content>
                  </paragraph>
                  <paragraph>See new warning information</paragraph>
                  <paragraph>
                     <content styleCode="bold">Treats Frequent Heartburn</content>
                  </paragraph>
                  <paragraph>
                     <content styleCode="bold">Nexium<sup>®</sup>
                     </content>
                     <br/>
                     <content styleCode="bold">24HR</content>
                     <br/>esomeprazole magnesium<br/>delayed-release capsules<br/>20 mg/acid reducer</paragraph>
                  <paragraph>
                     <content styleCode="bold">Clear Minis™</content>
                  </paragraph>
                  <paragraph>May take 1 to 4 days for full effect</paragraph>
                  <paragraph>
                     <content styleCode="bold">14</content>
                     <br/>
                     <content styleCode="bold">CAPSULES</content>
                     <br/>
                     <content styleCode="bold">One 14-day course of treatment</content>
                  </paragraph>
                  <paragraph>000078392 Front Carton</paragraph>
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               <effectiveTime value="20220602"/>
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                     <text>Nexium 24HR Clear Minis 14 ct</text>
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