Elanco US Inc.

Advantus IMIDACLOPRID IMIDACLOPRID IMIDACLOPRID red TRAPEZOID Advantus IMIDACLOPRID IMIDACLOPRID IMIDACLOPRID red TRAPEZOID

advantus is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.

advantus contains 7.5 mg or 37.5 mg of imidacloprid.

advantus kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.

Not for human use. Keep this and all drugs out of reach of children. Keep advantus in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.

Side effects seen with this drug include vomiting, decreased appetite, decreased energy, soft stools and difficulty walking.

You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Do not give to puppies younger than 10 weeks of age or to dogs weighing less than 4 pounds. Do not give more than one tablet a day. Use the table to find the right dose for your dog:

*If your dog becomes re-infested, you can safely repeat treatment as often as once a day.
Dosing Table
Body Weight	Dose*	Soft Chew Strength
4-22 lbs	One Soft Chew	7.5 mg imidacloprid
23-110 lbs	One Soft Chew	37.5 mg imidacloprid

To give advantus, place the soft chew directly in your dog's mouth or allow your dog to take the soft chew from your hand. Watch closely to ensure your dog swallows the soft chew. A single dose kills adult fleas on your dog. Because advantus does not have an effect on fleas in the environment, your dog may become re-infested with fleas. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. Contact your veterinarian if you have any questions about flea infestations on your dog. Treat all pets in your household with a flea protection product. advantus should only be given to dogs.

For product questions or to report side effects, call Elanco at 888-545-5973. For additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or http://www.fda.gov/reportanimalae

•Contact your veterinarian if your dog ingests more than the recommended dose of advantus. •advantus has not been tested in pregnant or nursing dogs. •advantus starts to kill fleas within 1 hour. A study demonstrated that advantus achieves greater than 96% effectiveness against adult fleas within 4 hours. •advantus may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, de-worming medications and shampoos. •advantus does not protect against ticks or mosquitoes.

Treatment of flea infestations is important to your dog's health. Fleas in your dog's environment can re-infest your dog. Therefore, you may need to treat with advantus more than one time. The following diagram illustrates the flea's life cycle and where advantus works: Fleas reproduce rapidly. A single female flea may produce up to 2,000 eggs over her lifetime. Eggs hatch and may grow into adults in only three weeks. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog's coat. Within days, larvae hatch from these eggs and live undetected in your dog's surroundings, such as in the carpet and bedding. Fleas can emerge to re-infest your pet, continuing the life cycle. When these new fleas are seen on your dog, treat with advantus. If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian. Figure

Store at temperatures between 68° and 77°F (20°-25°C).

advantus is available in two strengths: 7.5 mg or 37.5 mg imidacloprid. Both strengths are packaged in 7 count bottles containing 7 flavored soft chews or 30 count bottles containing 30 flavored soft chews. Approved by FDA under NADA # 141-435 Manufactured for:
Elanco US Inc.
Greenfield, IN 46140 U.S.A. 90207038_PA600215X Revised: January 2022 Made in Spain. advantus, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. © 2022 Elanco or its affiliates TAKE TIME OBSERVE LABEL DIRECTIONS ElancoTM

ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
4–22 lbs. Elanco
advantusTM (imidacloprid) soft chew 7.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 7
SOFT
CHEWS Each soft chew contains
7.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 7.5 mg Carton Label

ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
4–22 lbs. Elanco
advantusTM (imidacloprid) soft chew 7.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 7
SOFT
CHEWS Each soft chew contains
7.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 7.5 mg 7 Soft Chews Bottle Label

Peel
Here ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
4–22 lbs. Elanco
advantus™ (imidacloprid) soft chew 7.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 30
SOFT
CHEWS Each soft chew contains 7.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 7.5 mg 30 Soft Chews Bottle Label

ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
23–110 lbs. Elanco
advantusTM (imidacloprid) soft chew 37.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 7
SOFT
CHEWS Each soft chew contains
37.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 37.5 mg Carton Label

ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
23–110 lbs. Elanco
advantusTM (imidacloprid) soft chew 37.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 7
SOFT
CHEWS Each soft chew contains
37.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 37.5 mg 7 Soft Chews Bottle Label

Peel
Here ORAL FLEA
TREATMENT FOR
DOGS 10 WEEKS
OF AGE AND
OLDER,
BETWEEN
23–110 lbs. Elanco
advantus™ (imidacloprid) soft chew 37.5 mg ORAL FLEA TREATMENT Starts to kill fleas on dogs
within one hour 30
SOFT
CHEWS Each soft chew contains 37.5 mg of imidacloprid. Approved by FDA under NADA # 141-435 KEEP OUT OF REACH
OF CHILDREN Advantus (imidacloprid) soft chew 37.5 mg 30 Soft Chews Bottle Label