GlaxoSmithKline Consumer Healthcare Holdings (US) LLC

Nexium 24HR esomeprazole magnesium ESOMEPRAZOLE MAGNESIUM ESOMEPRAZOLE STARCH, CORN CROSPOVIDONE (120 .MU.M) D&C RED NO. 27 FD&C BLUE NO. 2 FD&C RED NO. 40 GLYCERYL MONOSTEARATE HYDROXYPROPYL CELLULOSE (1600000 WAMW) HYPROMELLOSE, UNSPECIFIED MAGNESIUM STEARATE METHACRYLIC ACID - METHYL METHACRYLATE COPOLYMER (1:1) MICA MICROCRYSTALLINE CELLULOSE PARAFFIN POLYETHYLENE GLYCOL, UNSPECIFIED POLYSORBATE 80 SODIUM STEARYL FUMARATE SUCROSE TALC TITANIUM DIOXIDE TRIETHYL CITRATE N;20;mg

Active ingredient (in each tablet) Esomeprazole 20 mg (Each delayed-release tablet corresponds to 22.3 mg esomeprazole magnesium trihydrate)

Purpose Acid reducer

Uses •treats frequent heartburn (occurs 2 or more days a week) •not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect

Warnings

•Do not use if you are allergic to esomeprazole •Esomeprazole may cause severe skin reactions. Symptoms include: •skin reddening •blisters •rash If an allergic reaction occurs, stop use and seek medical attention right away.

•trouble or pain swallowing food, vomiting with blood, or bloody or black stools •heartburn with lightheadedness, sweating or dizziness •chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness •frequent chest pain These may be signs of a serious condition. See your doctor.

•had heartburn over 3 months. This may be a sign of a more serious condition. •frequent wheezing, particularly with heartburn •unexplained weight loss •nausea or vomiting •stomach pain

Ask a doctor or pharmacist before use if you are •taking a prescription drug. Acid reducers may interact with certain prescription drugs.

•your heartburn continues or worsens •you need to take this product for more than 14 days •you need to take more than 1 course of treatment every 4 months •you get diarrhea •you develop a rash or joint pain

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions •adults 18 years of age and older •this product is to be used once a day (every 24 hours), every day for 14 days •may take 1 to 4 days for full effect
14-Day Course of Treatment •swallow 1 tablet with a glass of water before eating in the morning •take every day for 14 days •do not take more than 1 tablet a day •swallow whole. Do not crush or chew tablets. •do not use for more than 14 days unless directed by your doctor   Repeated 14-Day Courses (if needed) •you may repeat a 14-day course every 4 months • do not take for more than 14 days or more often than every 4 months unless directed by a doctor •children under 18 years of age: ask a doctor before use. Heartburn in children may sometimes be caused by a serious condition.

Other Information •read the directions and warnings before use •keep the carton. It contains important information. •store at 20-25°C (68-77°F)

Inactive ingredients corn starch, crospovidone, D&C red no. 27 aluminum lake, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer, mica, microcrystalline cellulose, paraffin, polyethylene glycol, polysorbate 80, sodium stearyl fumarate, sucrose, talc, titanium dioxide, triethyl citrate

Questions or comments? call toll-free weekdays 9 AM to 5 PM EST at 1-866-226-1600

KEEP CARTON FOR COMPLETE WARNINGS AND IMPORTANT INFORMATION. Do Not Use if seal under bottle cap imprinted with “SEALED for YOUR PROTECTION” or yellow band around the center of each capsule is broken or missing. Tips for Managing Heartburn •Avoid foods or drinks that are more likely to cause heartburn, such as rich, spicy, fatty •and fried foods, chocolate, caffeine, alcohol and even some acidic fruits and vegetables. •Eat slowly and do not eat big meals. •Do not eat late at night or just before bedtime. •Do not lie flat or bend over soon after eating. •Raise the head of your bed. •Wear loose-fitting clothing around your stomach. •If you are overweight, lose weight. •If you smoke, quit smoking Distributed by: GSK Consumer Healthcare, Warren, NJ 07059 ©2022 GSK group of companies or its licensor Made in France For most recent product information, visit www.Nexium24HR.com Nexium is a registered trademark of AstraZeneca AB and is used under license.

NDC 0573-2451-14 See new warning information Treats Frequent Heartburn Nexium®
24HR esomeprazole magnesium delayed-release tablets
20 mg/acid reducer Tablets May take 1 to 4 days for full effect 14
TABLETS One 14-day course of treatment 000078388 Front Carton Nexium 24 Hr Tablets 14ct