It was reported via a medwatch report that the patient had undergone two prior platelet rich plasma injections in the past, one in 2018 and the second in 2019.The physician reported that the patient did extremely well afterwards with great relief of their pain.The physician completed a third prp injection on the patient's right knee using abs-10063 (lot: 2020030011) under ultrasound guidance.The injection went well and was done with sterile technique.The patient did well for the first few days.However, the patient then started experiencing increased pain and swelling without redness, warmth, fevers or chills.Fluid was drained and sent for analysis and thought to be a pseudoseptic inflammatory reaction.Culture later grew out staph lugdunensis after a few days in thio broth tube only, and thought to be skin contaminant.The patient did not improve and was sent to the emergency room.The patient was seen by an ortho and also thought to be an inflammatory reaction.Pain continued and knee was once again drained and eventually grew out staph lugdunensis and the patient was sent back to the er.The patient was seen by infectious disease who thought the issue was septic arthritis.The patient underwent surgical washout and was treated with a prolonged course of iv antibiotics.
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