The article, "delayed hemolytic transfusion reaction after mitra! valve replacement : report of a case", was reviewed.The research article presents a case study of delayed hemolytic transfusion reaction (dhtr) after mitral valve replacement (mvr).A (b)(6) woman with a history of blood transfusion was admitted for mvr.Preoperative laboratory test were negative for irregular antibodies except anti-dia.She underwent mvr using a mechanical prosthesis with a 27mm sjm mechanical heart valve.Compatible blood products were transfused perioperatively.On post-operative day 13.She developed hemoglobinuria mid anemia with elevated serum total bilirubin and lactic dehydrogenase levels.Transesophageal echocardiography showed trivial transvalvular leakage.Laboratory test successfully identified another irregular antibody, anti-jkb antibody.The patient had a jkb negative blood transfusion.And did not need re-operation.Later.She recovered with no signs of hemolysis.The article concluded that since anti-jk1'antibody gets undetectable within a few months, it is difficult to find out before surgery.As hemolysis following cardiac surgery is more commonly associated with prostheses and extracorporeal circulation than dhtr.Physicians should however be aware of this unusual complication especially in patients who undergo blood transfusions.The primary author of the article is shogo isomura, department of cardiovascular surgery, nagano chuo hospital, japan, 380-0814 nagano, 1570.
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As reported in a research article, a patient had hemoglobinuria mid anemia 13 days after replacement of their mitral valve with a mechanical heart valve.The valve was found to have trivial transvalvular leakage, and the patient recovered.Further laboratory testing revealed that the patient had anti-jkb antibody, which can lead to delayed hemolytic transfusion reaction.A more comprehensive assessment could not be performed as the event was non-contemporaneously reported through a literature review and no device was received for analysis.
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