A 68-year old male patient with newly diagnosed glioblastoma (gbm) began optune therapy on (b)(6) 2022.Novocure received a report on (b)(6) 2022, that the patient experienced a seizure on (b)(6) 2022, that required hospitalization.Optune therapy was temporarily discontinued.The patient presented with altered mental status and unable to confirm medical history.The patient was administered intravenous (iv) anti-seizure medication (lacosamide 200 mg, levetiracetam 2,000 mg).Continuous electroencephalography (eeg) confirmed abnormal findings consistent with seizure activity.On (b)(6) 2022, the prescribing physician reported the patient did not have a history of seizures.The brain mri did not show evidence of disease progression and eeg showed abnormal activity confirming seizure.Reportedly, the patient was discharged home in stable condition and prescribed levetiracetam.The physician noted the patient was prescribed temozolomide and unsure if the seizure was related to optune therapy or temozolomide.
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