The article, "thrombosed stuck mitral valve during advanced mechanical circulatory support for post-cardiotomy shock", was reviewed.This article presented a case study of a 52 year old patient with a previous diagnosis of idiopathic dilated cardiomyopathy and history of hepatitis c.The patient was admitted to the hospital for decompensated acute heart failure with severe left ventricle (lv) dysfunction and mitral regurgitation (mr).The patient was not a heart transplant candidate because of their history of drug abuse.The patient was dobutamine dependent with a intra-aortic balloon pump (iabp).Urgent mitral valve replacement (mvr) was required due to heart failure that was difficult to control.A 31 mm sjm mechanical heart valve was implanted and a 32 mm non-abbott tricuspid annuloplasty ring was implanted.The patient was unsuccessfully weaned from cardiopulmonary bypass (cpb) due to severe right ventricle (rv) and lv dysfunctions.The iabp was removed and replaced with ecpella, va-ecmo with left femoral cannulation for rv failure and severe hypoxia.Also impella 2.5 via the right femoral artery to unload the impaired lv.An activated clotting time of 160 seconds was attempted to be maintained in the patient 1 day after the implant procedure but the patient required four re-operations for bleeding with blood transfusions and temporary discontinuation of heparin.On postoperative day 12, the ecpella was changed to a extracorporeal biventricular assist device (ex-bivad) due to poor recovery of both ventricular function, persistently poor lung function and signs of multiple organ failure.The patient also had increasing creatinine and bilirubin levels.Echocardiographic and fluoroscopic images revealed that the leaflets were stuck on the 31 mm sjm mechanical heart valve.Therefore on postoperative day 18, a re-mvr was performed using a 27 mm non-abbott valve.During the explant of the 31 mm mechanical heart valve, it was confirmed that the leaflets stuck were due to thrombus.The patient was slowly weaned from ex-bivad, and the lv contractions improved.The patient was extubated on postoperative day 33 and was transferred to rehab 70 days after ex-bivad weaning.The patient well functioning mitral bioprosthesis on echocardiography, although left ventricular ejection fraction had not improved (32%).The patient was alive uneventfully at their 2 year follow up.The article concluded that it is important to balance the effects of anticoagulation on advanced mechanical circulatory support, against the side effects of bleeding, especially in the post-cardiotomy patients with bleeding tendency.[the primary and corresponding author is yoshiyuki takami, md, department of cardiovascular surgery, fujita health university school of medicine, 1-98 dengakugakubo, kutsukake, toyoake, aichi 470-1192, japan, with email address: mytakami@fujita-hu.Ac.Jp].
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Summarized patient outcomes/complications of master series mechanical heart valve implant were reported in a research article in a subject population with multiple co-morbidities idiopathic dilated cardiomyopathy,(b)(4).Moderate tricuspid regurgitation (tr) with right ventricular (rv) dysfunction and acute heart failure.Some of the complications reported were mitral regurgitation, bleeding persistently poor lung function, signs of multiple organ failure and explant due to leaflets stuck due to thrombus; these complications are anticipated for the procedure and subject population.A more comprehensive assessment could not be performed as the event was non-contemporaneously reported through a literature review and no device or individual patient information was received for analysis.
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