A 40-year-old male with a high grade glioma started optune therapy on (b)(6) 2023.Novocure was informed on (b)(6) 2023, that the patient was hospitalized earlier that day due to a seizure.The patient noted he had discontinued an unspecified seizure medication the month prior.The patient's health care provider (hcp) was made aware and optune therapy was temporarily discontinued.On (b)(6) 2023, the hcp reported that the patient did not have a history of seizure.In addition, levetiracetam was previously prescribed during his hospital admission in (b)(6) 2023.In the emergency department (ed) following the seizure the patient was administered intravenous (iv) levetiracetam 1 gram and upon hospital admission 500mg iv every 12 hours.Lorazepam was prescribed as needed for breakthrough seizures.The patient was discharged on (b)(6) 2023, on oral levetiracetam 500mg bid, and advised to resume dexamethasone and follow up with radiation oncology and neurosurgery.The hcp assessed that the exact cause of the event was unknown, the event may or may not have involved underlying disease and/or optune therapy.
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