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Current and Resolved Drug Shortages and Discontinuations Reported to FDA

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Bupivacaine Hydrochloride and Epinephrine Injection
Status: Currently in Shortage
»Date first posted: 02/20/2018
»Therapeutic Categories: Anesthesia

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Fresenius Kabi USA, LLC (Revised 09/14/2022)

Company Contact Information:
888-386-1300

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Sensorcaine w/EPI 0.25% (125 mg per 50 mL) (2.5 mg per mL) MDV (NDC 63323-461-57) Backordered. Next release October 2022. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine w/EPI 0.5% (250 mg per 50 mL) (5 mg per mL) MDV (NDC 63323-463-57) Backordered. Next release October 2022. Demand increase for the drug
Sensorcaine MPF w/EPI 0.25% (25 mg per 10 mL) (2.5 mg per mL) SDV (NDC 63323-468-17) Backordered. Next release October 2022. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine MPF w/EPI .25% (75 mg per 30 mL) (2.5 mg per mL) SDV (NDC 63323-468-37) Backordered. Next release October 2022. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (50 mg per 10 mL) (5 mg per mL) SDV (NDC 63323-462-17) Backordered. Next release October 2022. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (150 mg per 30 mL) (5 mg per mL) SDV (NDC 63323-462-37) Backordered. Next release October 2022. Check wholesalers for inventory. Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (150 mg per 30 mL) (5 mg per mL) Sterile-Pak, SDV (NDC 63323-462-31) Backordered. Next release date not available at this time. Demand increase for the drug
Sensorcaine MPF w/EPI 0.75% (225 mg per 30 mL) (7.5 mg per mL) SDV (NDC 63323-460-37) Backordered. Next release not available at this time. Demand increase for the drug

Hospira, Inc. (Revised 09/12/2022)

Company Contact Information:
844-646-4398

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
25 mg/10 mL (2.5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9042-01) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
75 mg/30 mL (2.5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9042-17) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
125 mg/50 mL (2.5 mg/mL); Multiple Dose Glass Fliptop Vial (NDC 00409-9043-01) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
50 mg/10 mL (5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9045-01) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
150 mg/30 mL (5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9045-17) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
250 mg/50 mL (5 mg/mL); Multiple Dose Glass Fliptop Vial (NDC 00409-9046-01) Next Delivery: April 2023; Estimated Recovery: December 2023 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 25 mg/10 mL (2.5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1746-10) Next Delivery: October 2022; Estimated Recovery: March 2023 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 75 mg/30 mL (2.5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1746-30) Next Delivery: September 2022; Estimated Recovery: March 2023 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 50 mg/10 mL (5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1749-10) Next Delivery: October 2022; Estimated Recovery: January 2023 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 150 mg/30 mL (5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1749-29) Next Delivery: September 2022; Estimated Recovery: March 2023 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 125 mg/50 mL (2.5 mg/mL 1:200,000); Multiple Dose Glass Fliptop Vial (NDC 00409-1752-50) Next Delivery and Estimated Recovery: September 2022 Shortage per Manufacturer: Manufacturing Delay Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 250 mg/50 mL (5 mg/mL 1:200,000); Multiple Dose Glass Fliptop Vial (NDC 00409-1755-50) Limited Supply Available. Next Delivery: September 2022; Estimated Recovery: October 2022 Shortage per Manufacturer: Manufacturing Delay Other
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