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FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

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Bupivacaine Hydrochloride and Epinephrine Injection
Status: Currently in Shortage
»Date first posted: 02/20/2018
»Therapeutic Categories: Anesthesia

Fresenius Kabi USA, LLC (Revised 03/10/2023)

Company Contact Information:
888-386-1300

Presentation	Availability and Estimated Shortage Duration	Related Information	Shortage Reason (per FDASIA)
Sensorcaine w/EPI 0.25% (125 mg per 50 mL) (2.5 mg per mL) MDV (NDC 63323-461-57)	Next release not available at this time.		Demand increase for the drug
Sensorcaine w/EPI 0.5% (250 mg per 50 mL) (5 mg per mL) MDV (NDC 63323-463-57)	Available	Check wholesalers for inventory.	Demand increase for the drug
Sensorcaine MPF w/EPI 0.25% (25 mg per 10 mL) (2.5 mg per mL) SDV (NDC 63323-468-17)	Backordered. Next release May 2023.	Check wholesalers for inventory.	Demand increase for the drug
Sensorcaine MPF w/EPI .25% (75 mg per 30 mL) (2.5 mg per mL) SDV (NDC 63323-468-37)	Backordered. Next release March 2023.	Check wholesalers for inventory.	Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (50 mg per 10 mL) (5 mg per mL) SDV (NDC 63323-462-17)	Backordered. Next release April 2023.	Check wholesalers for inventory.	Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (150 mg per 30 mL) (5 mg per mL) SDV (NDC 63323-462-37)	Backordered. Next release March 2023.	Check wholesalers for inventory.	Demand increase for the drug
Sensorcaine MPF w/EPI 0.5% (150 mg per 30 mL) (5 mg per mL) Sterile-Pak, SDV (NDC 63323-462-31)	Backordered. Next release date not available at this time.		Demand increase for the drug
Sensorcaine MPF w/EPI 0.75% (225 mg per 30 mL) (7.5 mg per mL) SDV (NDC 63323-460-37)	Backordered. Next release not available at this time.		Demand increase for the drug

Hospira, Inc., a Pfizer company (Revised 03/17/2023)

Company Contact Information:
844-646-4398

Presentation	Availability and Estimated Shortage Duration	Related Information	Shortage Reason (per FDASIA)
25 mg/10 mL (2.5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9042-01)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
75 mg/30 mL (2.5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9042-17)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
125 mg/50 mL (2.5 mg/mL); Multiple Dose Glass Fliptop Vial (NDC 00409-9043-01)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
50 mg/10 mL (5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9045-01)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
150 mg/30 mL (5 mg/mL); Single Dose Glass Teartop Vial (NDC 00409-9045-17)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
250 mg/50 mL (5 mg/mL); Multiple Dose Glass Fliptop Vial (NDC 00409-9046-01)	Next Delivery: February 2024; Estimated Recovery: March 2024	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 25 mg/10 mL (2.5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1746-10)	Next Delivery: August 2023; Estimated Recovery: June 2024	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 75 mg/30 mL (2.5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1746-30)	Next Delivery: August 2023; Estimated Recovery: June 2024	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 50 mg/10 mL (5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1749-10)	Next Delivery: April 2023; Estimated Recovery: June 2024	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 150 mg/30 mL (5 mg/mL 1:200,000); Single Dose Glass Fliptop Vial (NDC 00409-1749-29)	Next Delivery: September 2023; Estimated Recovery: June 2024	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 125 mg/50 mL (2.5 mg/mL 1:200,000); Multiple Dose Glass Fliptop Vial (NDC 00409-1752-50)	Next Delivery and Estimated Recovery: March 2023	Shortage per Manufacturer: Manufacturing Delay	Other
Marcaine with Epinephrine 1:200,000 as the bitartrate 250 mg/50 mL (5 mg/mL 1:200,000); Multiple Dose Glass Fliptop Vial (NDC 00409-1755-50)	Next Delivery and Estimated Recovery: March 2023	Check Wholesaler for Availability Shortage per Manufacturer: Manufacturing Delay	Other

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