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FDA Drug Shortages

Current and Resolved Drug Shortages and Discontinuations Reported to FDA

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Epinephrine Bitartrate, Lidocaine Hydrochloride Injection
Status: Currently in Shortage
»Date first posted: 02/22/2012
»Therapeutic Categories: Anesthesia; Pediatric

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Fresenius Kabi USA, LLC (Revised 10/06/2026)

Company Contact Information:
888-386-1300

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Xylocaine, Injection, .01 mg/1 mL; 10 mg/1 mL (NDC 63323-482-17) Available Check wholesalers for inventory Demand increase for the drug
Xylocaine, Injection, .005 mg/1 mL; 10 mg/1 mL (NDC 63323-487-17) Available Check wholesalers for inventory
Xylocaine, Injection, .005 mg/1 mL; 15 mg/1 mL (NDC 63323-488-17) Unavailable Next release September 2026. Check wholesalers for inventory. Demand increase for the drug
Xylocaine, Injection, .005 mg/1 mL; 20 mg/1 mL (NDC 63323-489-17) Available Check wholesalers for inventory
Xylocaine, Injection, .005 mg/1 mL; 5 mg/1 mL (NDC 63323-481-57) Unavailable Next release September 2026. Check wholesalers for inventory. Demand increase for the drug
Xylocaine, Injection, .01 mg/1 mL; 10 mg/1 mL (NDC 63323-482-27) Available Check wholesalers for inventory
Xylocaine, Injection, .01 mg/1 mL; 10 mg/1 mL (NDC 63323-482-57) Unavailable Next release September 2026. Check wholesalers for inventory. Other
Xylocaine, Injection, .01 mg/1 mL; 20 mg/1 mL (NDC 63323-483-27) Available Check wholesalers for inventory
Xylocaine, Injection, .01 mg/1 mL; 20 mg/1 mL (NDC 63323-483-57) Available Check wholesalers for inventory
Xylocaine, Injection, .005 mg/1 mL; 10 mg/1 mL (NDC 63323-487-37) Available Check wholesalers for inventory
Xylocaine, Injection, .005 mg/1 mL; 15 mg/1 mL (NDC 63323-488-37) Available Check wholesalers for inventory
Xylocaine, Injection, .005 mg/1 mL; 20 mg/1 mL (NDC 63323-489-27) Unavailable Next release September 2026. Check wholesalers for inventory. Other

Hospira, Inc., a Pfizer Company (Revised 09/22/2026)

Company Contact Information:
844-646-4398

Presentation Availability and Estimated Shortage Duration Related Information Shortage Reason (per FDASIA)
Lidocaine Hydrochloride And Epinephrine, Injection, 250 mg/50 mL (0.5%; 1:200,000) (NDC 0409-3177-01) Unavailable Next Delivery and Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 200 mg/20 mL (1%; 1:100,000) (NDC 0409-3178-01) Unavailable Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 300 mg/30 mL (1%; 1:100,000) (NDC 0409-3178-02) Unavailable Next Delivery: November 2026; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 500 mg/50 mL (1%; 1:100,000) (NDC 0409-3178-03) Limited Availability Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 75 mg/5 mL (1.5%; 1:200,000) (NDC 0409-1209-01) Unavailable Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 450 mg/30 mL (1.5%; 1:200,000) (NDC 0409-3181-01) Available
Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:100,000) (NDC 0409-3182-01) Unavailable Next Delivery and Estimated Recovery: December 2028; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride and Epinephrine, Injection, 600 mg/30 mL (2%; 1:100,000) (NDC 0409-3182-02) Limited Availability Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 1 g/50 mL (2%; 1:100,000) (NDC 0409-3182-03) Limited Availability Limited Supply Available. Next Delivery: May 2027; Estimated Recovery: June 2027; Shortage per Manufacturer: Manufacturing Delay Other
Lidocaine Hydrochloride And Epinephrine, Injection, 400 mg/20 mL (2%; 1:200,000) (NDC 0409-3183-01) Available
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