Current and Resolved Drug Shortages and Discontinuations Reported to FDA
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Methylprednisolone Acetate Injection
Status: Currently in Shortage
»Date first posted:
12/15/2021
»Therapeutic Categories: Rheumatology
Amneal Pharmaceuticals (Revised 11/07/2025)
| Presentation | Availability and Estimated Shortage Duration | Related Information | Shortage Reason (per FDASIA) |
|---|---|---|---|
| Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1) | Limited Availability | Next supply: week of 11/17/2025 | Other |
| Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5) | Available | Next supply: week of 11/24/2025 | Other |
| Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1) | Available | Currently product is under backorder as per current demand. Next supply: week of 11/24/2025 | Other |
| Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5) | Available | Currently product is under backorder as per current demand. Next supply: week of 11/24/2025 | Other |
Eugia US LLC (Revised 10/17/2025)
| Presentation | Availability and Estimated Shortage Duration | Related Information | Shortage Reason (per FDASIA) |
|---|---|---|---|
| Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01) | Unavailable | On backorder. Recovery: TBD. Check wholesalers for inventory | Demand increase for the drug |
| Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01) | Unavailable | On backorder. Recovery: TBD. Check wholesalers for inventory | Demand increase for the drug |
Par Pharmaceutical, Inc. (Reverified 11/05/2025)
| Presentation | Availability and Estimated Shortage Duration | Related Information | Shortage Reason (per FDASIA) |
|---|---|---|---|
| Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 42023-240-01) | Available |
Pfizer Inc. (Reverified 10/23/2025)
| Presentation | Availability and Estimated Shortage Duration | Related Information | Shortage Reason (per FDASIA) |
|---|---|---|---|
| Depo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01) | Available | ||
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02) | Available | ||
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03) | Unavailable | Next Delivery: October 2025; Estimated Recovery: December 2025 | Demand increase for the drug |
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51) | Available | ||
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52) | Limited Availability | Limited Supply Available. Next Delivery: November 2025; Estimated Recovery: December 2025 | Other |
| Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02) | Available | ||
| Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12) | Unavailable | Next Delivery: October 2025; Estimated Recovery: December 2025 | Demand increase for the drug |
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01) | Limited Availability | Limited Supply Available. Next Delivery: October 2025; Estimated Recovery: March 2026 | Demand increase for the drug |
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03) | Limited Availability | Limited Supply Available. Next Delivery: October 2025; Estimated Recovery: December 2025 | Other |
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22) | Available | ||
| Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23) | Available | ||
| Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01) | Unavailable | Next Delivery: October 2025; Estimated Recovery: December 2025 | Other |
| Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03) | Unavailable | Next Delivery: October 2025; Estimated Recovery: June 2026 | Other |
Sagent Pharmaceuticals (Reverified 08/26/2025)
| Presentation | Availability and Estimated Shortage Duration | Related Information | Shortage Reason (per FDASIA) |
|---|---|---|---|
| Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10) | Available | ||
| Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05) | Available | ||
| Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05) | Available |